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AB150683

Phosphotungstic Acid Hematoxylin (PTAH) Stain Kit (Connective Tissue Stain)

Phosphotungstic Acid Hematoxylin (PTAH) Stain Kit (Connective Tissue Stain)

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(1 Publication)

PTAH Stain Kit (Connective Tissue Stain) is intended for use in the histological visualization of collagen, striated muscle, glial fibers and collagen without using Zenker's Fixative containing mercuric chloride.
3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Phosphotungstic Acid Hematoxylin (PTAH) Stain Kit (Connective Tissue Stain) (AB150683)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Phosphotungstic Acid Hematoxylin (PTAH) Stain Kit (Connective Tissue Stain) (AB150683)

Staining using ab150683 - Phosphotungstic acid Hematoxylin (PTAH) Stain Kit.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Phosphotungstic Acid Hematoxylin (PTAH) Stain Kit (Connective Tissue Stain) (AB150683)
  • IHC-P

Lab

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Phosphotungstic Acid Hematoxylin (PTAH) Stain Kit (Connective Tissue Stain) (AB150683)

ab150683 (Phosphotungstic Acid Hematoxylin (PTAH) Stain) staining striated muscle (blue) and collagen (red) in formalin fixed paraffin embedded normal human muscle

*Tissue obtained from the Human Research Tissue Bank, supported by the NIHR Cambridge Biomedical Research Centre.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Phosphotungstic Acid Hematoxylin (PTAH) Stain Kit (Connective Tissue Stain) (AB150683)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Phosphotungstic Acid Hematoxylin (PTAH) Stain Kit (Connective Tissue Stain) (AB150683)

ab150683 Phosphotungstic Acid Hematoxylin (PTAH) Stain Kit (Connective Tissue Stain) staining formalin-fixed-paraffin embedded human skeletal muscle.

Key facts

サンプルタイプ

Tissue sections

製品の詳細

The PTAH Stain Kit (Connective Tissue Stain) is intended for use in the histological visualization of collagen, striated muscle, glial fibers and collagen without using Zenker's Fixative containing mercuric chloride.

This kit may be used on formalin-fixed, paraffin-embedded or frozen sections.

Other products for staining tissue sections

Find more kits and reagents in the special stains guide, or products for antigen retrieval, blocking, signal amplification, visualization, counterstaining, and mounting in the IHC kits and reagents guide.

Staining Interpretation

Fibrin, striated muscle, glial fibers Blue
Collagen Brown/Red
Nuclei Blue

Control Tissue: Striated muscle.

製品内容

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出荷温度及び保存条件

出荷温度
Ambient - Can Ship with Ice
短期保存温度
Ambient
長期保存温度
Ambient
保管に関する情報
Ambient

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Connective tissue is a complex structural network that supports and connects other tissues and organs in the body. It is composed mainly of protein fibers such as collagen elastin and reticular fibers with a ground substance of proteoglycans and glycoproteins. Connective tissue varies in density and cellular composition and is abundant throughout the body. It is expressed in diverse forms like loose connective tissue dense connective tissue cartilage bone blood and lymph each with distinct cellular arrangements fulfilling specific mechanical roles.
Biological function summary

Connective tissue provides structural support protection and insulation to the body while also facilitating nutrient transport and waste removal. It plays an integral role in tissue repair and inflammation response. Connective tissue exists as part of a larger extracellular matrix complex interacting with cells through integrins and other cell-surface proteins. It serves as a scaffold for cellular attachment and migration significantly impacting the function of embedded cells like fibroblasts adipocytes and immune cells.

Pathways

Connective tissue is deeply involved in processes like the wound healing pathway and the inflammatory response pathway. Within these pathways it interacts with proteins such as matrix metalloproteinases (MMPs) which remodel extracellular matrix components during tissue repair. Connective tissue also connects with signaling molecules like cytokines which regulate the inflammatory response and influence tissue dynamics and repair mechanisms.

Connective tissue abnormalities are implicated in conditions like Ehlers-Danlos syndrome and Marfan syndrome which involve defects in the structure or synthesis of connective tissue proteins. Mutations affecting collagen a major protein in connective tissue contribute to the development of these disorders. Additionally alterations in connective tissue can play a role in fibrosis and related diseases where excessive connective tissue deposition leads to organ dysfunction. Understanding connective tissue's role in these conditions aids in comprehending its impact on overall tissue integrity and function.

製品プロトコール

文献 (1)

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