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AB197441

Human Cytokine 抗体 Array D (40 Targets) - Quantitative

Human Cytokine Antibody Array D (40 Targets) - Quantitative

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ab197441 can be used for quantitative measurement of 40 Human cytokines.

別名を表示する

UNQ868/PRO1885, ACE2, Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, Angiotensin-converting enzyme-related carboxypeptidase, Metalloprotease MPROT15, ACEH, ACE-related carboxypeptidase

3 Images
Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)
  • Multiplex Protein Detection

Supplier Data

Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)

Standard Curve obtained using Abcam Human Cytokine Antibody Array D (40 Targets) - Quantitative (ab197441).

Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)
  • Multiplex Protein Detection

Supplier Data

Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)

Array map for Abcam Human Cytokine Antibody Array D (40 Targets) - Quantitative (ab197441).

Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)
  • Multiplex Protein Detection

Supplier Data

Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)

Assay summary for Abcam Human Cytokine Antibody Array D (40 Targets) - Quantitative (ab197441).

Key facts

アッセイタイプ

Quantitative

交差種

Human

ターゲット

ACE2

target

検出方法

Fluorescent

アッセイプラットフォーム

Multiplex

サンプルタイプ

Tissue Lysate, Plasma, Cell culture media, Serum, Other biological fluids, Cell Lysate

製品の詳細

ab197441 can be used for quantitative measurement of 40 Human cytokines. Suitable for serum, plasma, cell culture media, other body fluids, cell and tissue lysates.
Targets names: ACE-2, Albumin, AMICA, ANG-4, BAFF, CA19-9, CD163, Clusterin, CRTAM, CXCL14, Cystatin C, Decorin , Dkk-3, DLL1, Fetuin A, aFGF, FOLR1, Furin, GASP-1, GASP-2, GCSF R, HAI-2, IL-17B R, IL-27, LAG-3 , LDL R, Pepsinogen I, RANK, RBP4, SOST, Syndecan-1, TACI, TFPI, TSP-1, TRAIL R2, TRANCE, Troponin I, uPA, VE-Cadherin, WISP-1.

Quantitative antibody arrays can be used to quantitate up to 40 cytokines with as little as 50 µL of sample. Arrays are available for 400 human and 200 mouse proteins. Each glass slide is spotted with 16 identical antibody arrays and is provided with a 16 well gasket to allow separate samples to be applied to each array. Each antibody is spotted in quadruplicate in each array. For reproducible quantitation, eight of the arrays are used with a cocktail of protein standards to produce a standard curve. The same 8 standard curve arrays can be used across multiple slides, allowing measurement of 22 experimental samples with 2 slides, 36 with 3 slides etc. For high through-put, 4 slides can be nested into a tray matching a standard microplate, allowing automated processing with a liquid handling workstation. Array processing can be completed within one working day (see workflow diagram below) and arrays can be analyzed with a wide number of laser glass slide array / gene microarray scanners. If you don’t have a suitable scanner then we recommend our membrane antibody arrays, which can be analyzed with any WB chemiluminescent reader. The standard is affinity purified. "

製品内容

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出荷温度及び保存条件

出荷温度
Blue Ice
短期保存温度
-20°C
長期保存温度
-20°C
保管に関する情報
-20°C

製品プロトコール

ターゲットの情報

Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis (PubMed : 27217402). Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II (PubMed : 10924499, PubMed : 10969042, PubMed : 11815627, PubMed : 14504186, PubMed : 19021774). Also removes the C-terminal residue from three other vasoactive peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin (PubMed : 10969042, PubMed : 11815627). Also cleaves other biological peptides, such as apelins (apelin-13, [Pyr1]apelin-13, apelin-17, apelin-36), casomorphins (beta-casomorphin-7, neocasomorphin) and dynorphin A with high efficiency (PubMed : 11815627, PubMed : 27217402, PubMed : 28293165). In addition, ACE2 C-terminus is homologous to collectrin and is responsible for the trafficking of the neutral amino acid transporter SL6A19 to the plasma membrane of gut epithelial cells via direct interaction, regulating its expression on the cell surface and its catalytic activity (PubMed : 18424768, PubMed : 19185582).. (Microbial infection) Acts as a receptor for human coronaviruses SARS-CoV and SARS-CoV-2, as well as human coronavirus NL63/HCoV-NL63.. Isoform 2. Non-functional as a carboxypeptidase.. Isoform 2. (Microbial infection) Non-functional as a receptor for human coronavirus SARS-CoV-2.
See full target information ACE2

追加のターゲット

,FGF1,ALB,JAML,ANGPT4,TNFSF13B,CD163,CLU,CRTAM,CXCL14,CST3,DCN,DLL1,AHSG,FOLR1,FURIN,,CSF3R,SPINT2,IL17RB,IL27,LAG3,Low-density lipoprotein receptor,TNFRSF11A,RBP4,SOST,SDC1,TNFRSF13B,TFPI,THBS1,TNFRSF10B,TNFSF11,TNNI2,Urokinase-type plasminogen activator,CDH5,CCN4
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