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リコンビナントRabMAb

Anti-PRKX 抗体 [EPR4840] (ab109389)

Submit a review Submit a question References (2)
Western blot - Anti-PRKX antibody [EPR4840] (ab109389)
  • Anti-PRKX antibody [EPR4840] (ab109389)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR4840] to PRKX
  • Suitable for: WB
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Carrier Free

製品の概要

  • 製品名

    Anti-PRKX antibody [EPR4840]
    PRKX 一次抗体 製品一覧

  • 製品の詳細

    Rabbit monoclonal [EPR4840] to PRKX

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: WBmore details
    適用なし: IHC-P or IP

  • 種交差性

    交差種: Human
    交差が予測される動物種: Mouse, Rat

  • 免疫原

    Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

  • ポジティブ･コントロール

    • Flow Cyt: permeabilized A549 cells; WB: A549, Jurkat, 293T, fetal kidney and fetal brain lysates.

  • 特記事項

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

製品の特性

  • 製品の状態

    Liquid

  • 保存方法

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

  • バッファー

    pH: 7.20
    Preservative: 0.05% Sodium azide
    Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant
  • Concentration information loading...

  • 精製度

    Protein A purified

  • ポリ/モノ

    モノクローナル

  • クローン名

    EPR4840

  • アイソタイプ

    IgG

  • 研究分野

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab109389の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
WB
1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
特記事項
WB
1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
追加情報
Is unsuitable for IHC-P or IP.

ターゲット情報

  • 組織特異性

    High levels in adult and fetal brain, kidney and lung; low levels in adult placenta, heart, liver, skeletal muscle, pancreas and fetal liver.

  • 関連疾患

    Note=A chromosomal aberration involving PRKX is a cause of sex reversal disorder. Translocation t(X;Y)(p22;p11) with PRKY. Chromosomal translocations proximal to PRKY account for about 30% of the cases of sex reversal disorder in XX males and XY females.

  • 配列類似性

    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
  • Information by UniProt

  • 参照データベース

    • 別名

      • PKX1 antibody
      • PRKX antibody
      • PRKX_HUMAN antibody
      • Protein kinase PKX1 antibody
      • Serine/threonine-protein kinase PRKX antibody
      see all

    画像

    • Western blot - Anti-PRKX antibody [EPR4840] (ab109389)
      Western blot - Anti-PRKX antibody [EPR4840] (ab109389)
      All lanes : Anti-PRKX antibody [EPR4840] (ab109389) at 1/1000 dilution

      Lane 1 : A549 cell lysates
      Lane 2 : Jurkat cell lysates
      Lane 3 : 293T cell lysates
      Lane 4 : Human fetal kidney lysates
      Lane 5 : Human fetal brain lysates

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 41 kDa

    • Anti-PRKX antibody [EPR4840] (ab109389)
      Anti-PRKX antibody [EPR4840] (ab109389)

    参考文献 (2)

    ab109389 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab109389 は 2 報の論文で使用されています。

    • Tang B  et al. PEA15 promotes liver metastasis of colorectal cancer by upregulating the ERK/MAPK signaling pathway. Oncol Rep 41:43-56 (2019). PubMed: 30365128
    • Ouyang C  et al. Transforming Growth Factor (TGF)-ß-activated Kinase 1 (TAK1) Activation Requires Phosphorylation of Serine 412 by Protein Kinase A Catalytic Subunit a (PKACa) and X-linked Protein Kinase (PRKX). J Biol Chem 289:24226-37 (2014). WB . PubMed: 25028512

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