Anti-POU4F3 抗体 (ab272626)
Key features and details
- Rabbit polyclonal to POU4F3
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-POU4F3 antibody
POU4F3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to POU4F3 -
由来種
Rabbit -
Tested Applications & Species
Application Species ICC/IF HumanIHC-P Human -
免疫原
Recombinant fragment corresponding to Human POU4F3 aa 100-200.
Database link: Q15319 -
ポジティブ・コントロール
- IHC-P: Human cerebral tissue. WB: U-2 OS.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
アプリケーション
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab272626 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
アプリケーション | Species |
---|---|
ICC/IF |
Human
|
IHC-P |
Human
|
All applications |
Mouse
Rat
|
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
|
|
IHC-P |
1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
特記事項 |
---|
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
IHC-P
1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
May play a role in determining or maintaining the identities of a small subset of visual system neurons. -
組織特異性
Brain. Seems to be specific to the retina. -
関連疾患
Defects in POU4F3 are the cause of deafness autosomal dominant type 15 (DFNA15) [MIM:602459]. DFNA15 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. -
配列類似性
Belongs to the POU transcription factor family. Class-4 subfamily.
Contains 1 homeobox DNA-binding domain.
Contains 1 POU-specific domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 5459 Human
- Entrez Gene: 18998 Mouse
- Entrez Gene: 364855 Rat
- Omim: 602460 Human
- SwissProt: Q15319 Human
- SwissProt: Q63955 Mouse
- Unigene: 553499 Human
- Unigene: 221181 Mouse
see all -
別名
- Brain specific homeobox/POU domain protein 3C antibody
- Brain-3C antibody
- Brain-specific homeobox/POU domain protein 3C antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-POU4F3 antibody (ab272626)
Paraffin-embedded formalin-fixed Human cerebral tissue stained for POU4F3 using ab272626 at 1/1000 in immunohistochemical analysis.
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PFA fixed, Triton X-100 permeablized human cell line U-2 OS labeling POU4F3 (green) using ab272626 at 2 ug/ml in ICC/IF analysis.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
参考文献 (0)
ab272626 は論文での使用が確認できていません。