Anti-PIP2 抗体 [KT10] (ab2335)
Key features and details
- Mouse monoclonal [KT10] to PIP2
- Suitable for: ICC/IF
- Isotype: IgG2b
製品の概要
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製品名
Anti-PIP2 antibody [KT10]
PIP2 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [KT10] to PIP2 -
由来種
Mouse -
特異性
This antibody cross reacts with Phosphatidic acid (<5.0%). -
アプリケーション
適用あり: ICC/IFmore details -
免疫原
Full length native protein (purified) corresponding to Bovine PIP2. Native Phosphatidylinositol-4,5-biphosphate (PIP2) from bovine spinal cord
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.1% Sodium azide
Constituents: PBS, 10% Fetal calf serum -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
KT10 -
アイソタイプ
IgG2b -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab2335の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC/IF |
Use at an assay dependent concentration.
TBS buffer is ideal. |
特記事項 |
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ICC/IF
Use at an assay dependent concentration. TBS buffer is ideal. |
ターゲット情報
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関連性
Phosphatidylinositol 4,5-biphosphate (PIP2) is a membrane phospholipid that has been implicated in a variety of cellular processes, including synaptic vesicle recycling and signal transduction pathways. PLCD4 hydrolyzes PIP2 to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3).
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (11)
ab2335 は 11 報の論文で使用されています。
- Ray AT et al. FGF signaling regulates development by processes beyond canonical pathways. Genes Dev 34:1735-1752 (2020). PubMed: 33184218
- Assil S et al. Plasmacytoid Dendritic Cells and Infected Cells Form an Interferogenic Synapse Required for Antiviral Responses. Cell Host Microbe 25:730-745.e6 (2019). PubMed: 31003939
- Suzuki H et al. Regulation of MC3T3-E1 differentiation by actin cytoskeleton through lipid mediators reflecting the cell differentiation stage. Biochem Biophys Res Commun 514:393-400 (2019). PubMed: 31047639
- Roman-Garcia S et al. Distinct Roles for Bruton's Tyrosine Kinase in B Cell Immune Synapse Formation. Front Immunol 9:2027 (2018). PubMed: 30237801
- Mkrtschjan MA et al. Lipid signaling affects primary fibroblast collective migration and anchorage in response to stiffness and microtopography. J Cell Physiol 233:3672-3683 (2018). PubMed: 29034471