Anti-PI4 kinase beta/PI4KB 抗体 [EPR3758(2)] (ab109418)
![Western blot - Anti-PI4 kinase beta/PI4KB antibody [EPR3758(2)] (ab109418)](https://www.abcam.co.jp/ps/products/109/ab109418/Images/ab109418-122244-anti-pi4-kinase-beta-antibody-epr37582-western-blot.jpg "Western blot - Anti-PI4 kinase beta/PI4KB antibody [EPR3758(2)] (ab109418)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR3758(2)] to PI4 kinase beta/PI4KB
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-PI4 kinase beta/PI4KB antibody [EPR3758(2)]
PI4 kinase beta/PI4KB 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR3758(2)] to PI4 kinase beta/PI4KB -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC,IHC-P or IP -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- HeLa, SH-SY5Y, BxPC-3 and Jurkat cell lysates
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR3758(2) -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab109418の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000 - 1/10000. Detects a band of approximately 100 kDa (predicted molecular weight: 91 kDa).
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| 特記事項 |
|---|
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WB
1/1000 - 1/10000. Detects a band of approximately 100 kDa (predicted molecular weight: 91 kDa). |
追加情報
Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
ターゲット情報
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機能
Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking. -
組織特異性
Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver. -
配列類似性
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
Contains 1 PI3K/PI4K domain.
Contains 1 PIK helical domain. -
細胞内局在
Endomembrane system. Mitochondrion outer membrane. Rough endoplasmic reticulum membrane. Golgi apparatus. Cytoplasm, perinuclear region. Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex. - Information by UniProt
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参照データベース
- Entrez Gene: 5298 Human
- Entrez Gene: 107650 Mouse
- Entrez Gene: 81747 Rat
- Omim: 602758 Human
- SwissProt: Q5VWB9 Human
- SwissProt: Q5VWC0 Human
- SwissProt: Q5VWC1 Human
- SwissProt: Q9UBF8 Human
see all -
別名
- DKFZp686O1820 antibody
- FLJ30129 antibody
- NPIK antibody
see all
画像
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Western blot - Anti-PI4 kinase beta/PI4KB antibody [EPR3758(2)] (ab109418)All lanes : Anti-PI4 kinase beta/PI4KB antibody [EPR3758(2)] (ab109418) at 1/1000 dilution
Lane 1 : HeLa cell lysate
Lane 2 : SH-SY5Y cell lysate
Lane 3 : BxPC-3 cell lysate
Lane 4 : Jurkat cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 91 kDa -
![Anti-PI4 kinase beta/PI4KB antibody [EPR3758(2)] (ab109418)](https://www.abcam.co.jp/ps/products/109/ab109418/Images/ab109418-2-benefits-of-recombinant-antibodies.png)
Anti-PI4 kinase beta/PI4KB antibody [EPR3758(2)] (ab109418)
データシートおよび資料
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Datasheet download
参考文献 (2)
ab109418 は 2 報の論文で使用されています。
- Xiong Y et al. STAT3-regulated long non-coding RNAs lnc-7SK and lnc-IGF2-AS promote hepatitis C virus replication. Mol Med Rep 12:6738-44 (2015). WB . PubMed: 26328522
- Téoulé F et al. The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication. J Virol 87:11031-46 (2013). PubMed: 23926333
