Anti-Perilipin A+B 抗体 (ab3527)

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Western blot - Anti-Perilipin A+B antibody (ab3527)

    Key features and details

    • Rabbit polyclonal to Perilipin A+B
    • Suitable for: WB
    • Reacts with: Mouse
    • Isotype: IgG

    製品の概要

    • 製品名

      Anti-Perilipin A+B antibody

    • 製品の詳細

      Rabbit polyclonal to Perilipin A+B

    • 由来種

      Rabbit

    • アプリケーション

      適用あり: WBmore details

    • 種交差性

      交差種: Mouse

    • 免疫原

      Synthetic peptide corresponding to Rat Perilipin A+B aa 1-100 (N terminal).

      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • ポジティブ･コントロール

      • WB: 3T3-L1 cell extract

    • 特記事項

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    製品の特性

    アプリケーション

    The Abpromise guarantee

    Abpromise保証は、 次のテスト済みアプリケーションにおけるab3527の使用に適用されます

    アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

    アプリケーション Abreviews 特記事項
    WB
    1/1000.
    特記事項
    WB
    1/1000.

    ターゲット情報

    • 関連性

      Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.

    • 細胞内局在

      Lipid droplet

    • 参照データベース

      • 別名

        • Lipid droplet associated protein antibody
        • PERIA antibody
        • PERIB antibody
        • Perilipin A antibody
        • Perilipin antibody
        • Perilipin B antibody
        • PLIN antibody
        see all

      画像

      • Western blot - Anti-Perilipin A+B antibody (ab3527)
        Western blot - Anti-Perilipin A+B antibody (ab3527)
        Anti-Perilipin A+B antibody (ab3527) + Cell extracts prepared from 3T3-L1 cells


        Western blot detection of perilipin A and B in 3T3-L1 cell extract using ab3527.

      参考文献 (2)

      ab3527 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

      ab3527 は 2 報の論文で使用されています。

      • Matushansky I  et al. A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas. Am J Pathol 172:1069-80 (2008). WB ; Human . PubMed: 18310505
      • Fernández-Veledo S  et al. Hyperinsulinemia induces insulin resistance on glucose and lipid metabolism in a human adipocytic cell line: paracrine interaction with myocytes. J Clin Endocrinol Metab 93:2866-76 (2008). PubMed: 18430774

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