Anti-Perilipin A+B 抗体 (ab3527)

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Key features and details

  • Rabbit polyclonal to Perilipin A+B
  • Suitable for: WB
  • Reacts with: Mouse, Rat
  • Isotype: IgG

製品の概要

  • 製品名

    Anti-Perilipin A+B antibody

  • 製品の詳細

    Rabbit polyclonal to Perilipin A+B

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: WBmore details

  • 種交差性

    交差種: Mouse, Rat

  • 免疫原

    Synthetic peptide corresponding to Rat Perilipin A+B aa 1-17 (N terminal).
    Sequence:

    MSMNKGPTLLDGDLPEQ


    (Peptide available as ab5010)

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab3527 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000.

ターゲット情報

  • 関連性

    Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.

  • 細胞内局在

    Lipid droplet

  • 参照データベース

    • 別名

      • Lipid droplet associated protein antibody
      • PERIA antibody
      • PERIB antibody
      • Perilipin A antibody
      • Perilipin antibody
      • Perilipin B antibody
      • PLIN antibody
      see all

    画像

    • Western blot - Anti-Perilipin A+B antibody (ab3527)
      Western blot - Anti-Perilipin A+B antibody (ab3527)
      Anti-Perilipin A+B antibody (ab3527) + Cell extracts prepared from 3T3-L1 cells


      Western blot detection of perilipin A and B in 3T3-L1 cell extract using ab3527.

    参考文献 (2)

    ab3527 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab3527 は 2 報の論文で使用されています。

    • Matushansky I  et al. A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas. Am J Pathol 172:1069-80 (2008). WB ; Human . PubMed: 18310505
    • Fernández-Veledo S  et al. Hyperinsulinemia induces insulin resistance on glucose and lipid metabolism in a human adipocytic cell line: paracrine interaction with myocytes. J Clin Endocrinol Metab 93:2866-76 (2008). PubMed: 18430774

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