Perilipin-1 タンパク質・ペプチド 製品一覧
Our Abpromise guarantee covers the use of ab5009 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat perilipin-1, catalog ab3526. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.
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Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
再構成>95% pure, lyophilized synthetic peptide. Reconstitute with 0.1 ml of distilled water.
- Lipid droplet associated protein
- Lipid droplet-associated protein
機能Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness.
配列類似性Belongs to the perilipin family.
翻訳後修飾Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet.
細胞内局在Lipid droplet. Lipid droplet surface-associated.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab5009 は 2 報の論文で使用されています。
- Seki M et al. Periostin-expressing cell-specific transforming growth factor-ß inhibition in pulmonary artery prevents pulmonary arterial hypertension. PLoS One 14:e0220795 (2019). PubMed: 31437169
- Linden JR et al. Clostridium perfringens Epsilon Toxin Causes Selective Death of Mature Oligodendrocytes and Central Nervous System Demyelination. MBio 6:e02513 (2015). IHC-P, ICC, IHC - Wholemount ; Mouse . PubMed: 26081637