PerCP/Cy5.5® Anti-Mannose Receptor 抗体 [15-2] (ab270683)
![Flow Cytometry - PerCP/Cy5.5® Anti-Mannose Receptor antibody [15-2] (ab270683)](https://www.abcam.co.jp/ps/products/270/ab270683/Images/ab270683-381527-antimannose-receptor-antibody-152-flow-monocytes-2.JPG "Flow Cytometry - PerCP/Cy5.5® Anti-Mannose Receptor antibody [15-2] (ab270683)")
Key features and details
- PerCP/Cy5.5® Mouse monoclonal [15-2] to Mannose Receptor
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PerCP/Cy5.5®. Ex: 482nm, Em: 690nm
- Isotype: IgG1
製品の概要
-
製品名
PerCP/Cy5.5® Anti-Mannose Receptor antibody [15-2]
Mannose Receptor 一次抗体 製品一覧 -
製品の詳細
PerCP/Cy5.5® Mouse monoclonal [15-2] to Mannose Receptor -
由来種
Mouse -
標識
PerCP/Cy5.5®. Ex: 482nm, Em: 690nm -
特異性
This antibody 15-2 (also known as MR15-2) recognizes an extracellular epitope of CD206 (macrophage mannose receptor, MMR), a 162-175 kDa type I transmembrane protein expressed mainly on macrophages, dendritic cells and hepatic or lymphatic endothelial cells, but not on monocytes.
-
Tested Applications & Species
See all applications and species dataApplication Species Flow Cyt Human
-
免疫原
Full length native protein (purified) corresponding to Human Mannose Receptor.
-
ポジティブ･コントロール
- Flow Cyt: Human monocytes.
-
特記事項
This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
pH: 7.4
Preservative: 0.0975% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Size exclusion -
ポリ/モノ
モノクローナル -
クローン名
15-2 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
-
Alternative Versions
アプリケーション
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab270683 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| アプリケーション | Species |
|---|---|
| Flow Cyt |
Human
|
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use 4µl for 106 cells.
The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in suspension. |
| 特記事項 |
|---|
|
Flow Cyt
Use 4µl for 106 cells. The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in suspension. |
ターゲット情報
-
機能
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. -
配列類似性
Contains 8 C-type lectin domains.
Contains 1 fibronectin type-II domain.
Contains 1 ricin B-type lectin domain. -
細胞内局在
Membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 4360 Human
- Omim: 153618 Human
- SwissProt: P22897 Human
- Unigene: 75182 Human
-
別名
- bA541I19.1 antibody
- C type lectin domain family 13 member D antibody
- C-type lectin domain family 13 member D antibody
see all
画像
-
Flow Cytometry - PerCP/Cy5.5® Anti-Mannose Receptor antibody [15-2] (ab270683)
Flow cytometry analysis of stimulated human monocytes (GM-CSF + IL-4) labeling Mannose Receptor (CD206) using ab270683. Surface staining.
Control is an anti-CD11c (BU15) APC antibody (10 μl reagent per million cells in 100 μl of cell suspension).
-
![Flow Cytometry - PerCP/Cy5.5® Anti-Mannose Receptor antibody [15-2] (ab270683)](https://www.abcam.co.jp/ps/products/270/ab270683/Images/ab270683-381526-antimannose-receptor-antibody-152-flow-graph-monocytes.JPG)
Flow Cytometry - PerCP/Cy5.5® Anti-Mannose Receptor antibody [15-2] (ab270683)Flow cytometry analysis of human stimulated monocytes (GM-CSF + IL-4) labeling Mannose Receptor (CD206) using ab270683 (Red). Surface staining.
Control: Non-stimulated lymphocytes (Black).
-
![Flow Cytometry - PerCP/Cy5.5® Anti-Mannose Receptor antibody [15-2] (ab270683)](https://www.abcam.co.jp/ps/products/270/ab270683/Images/ab270683-381525-antimannose-receptor-antibody-152-flow-monocytes.JPG)
Flow Cytometry - PerCP/Cy5.5® Anti-Mannose Receptor antibody [15-2] (ab270683)Flow cytometry analysis of stimulated human monocytes (GM-CSF + IL-4) labeling Mannose Receptor (CD206) using ab270683. Surface staining.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
参考文献 (0)
ab270683 は論文での使用が確認できていません。
