Anti-Pellino 1 抗体 (ab13812)
Key features and details
- Rabbit polyclonal to Pellino 1
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Pellino 1 antibody
Pellino 1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Pellino 1 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Rat, Xenopus laevis
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免疫原
Synthetic peptide:
SQSNSDTQSV QSTIS
conjugated to KLH, corresponding to amino acids 121-135 of Human Pellino 1 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
This antibody is affinity purified. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab13812の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (2) |
1/500 - 1/1000. Predicted molecular weight: 46 kDa.
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| 特記事項 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 46 kDa. |
ターゲット情報
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機能
Scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. Required for NF-kappa-B activation and IL-8 gene expression in response to IL-1. -
配列類似性
Belongs to the pellino family. - Information by UniProt
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参照データベース
- Entrez Gene: 57162 Human
- Entrez Gene: 67245 Mouse
- Entrez Gene: 305549 Rat
- Entrez Gene: 443954 Xenopus laevis
- Omim: 614797 Human
- SwissProt: Q96FA3 Human
- SwissProt: Q8C669 Mouse
- Unigene: 727530 Human
see all -
別名
- E3 ubiquitin-protein ligase pellino homolog 1 antibody
- PELI1 antibody
- PELI1_HUMAN antibody
see all
画像
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Western blot - Anti-Pellino 1 antibody (ab13812)All lanes : Anti-Pellino 1 antibody (ab13812) at 1/1000 dilution
Lane 1 : Lysates prepared from human Ramos cell line
Lane 2 : Lysates prepared from mouse Raw cell line
Predicted band size: 46 kDa
Western blot analysis of Pellino1 in human Ramos cell lysate (A) and mouse Raw cell lysate (B) using ab13812 at 1/1000
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (3)
ab13812 は 3 報の論文で使用されています。
- Thirunavukkarasu M et al. Disruption of VEGF Mediated Flk-1 Signaling Leads to a Gradual Loss of Vessel Health and Cardiac Function During Myocardial Infarction: Potential Therapy With Pellino-1. J Am Heart Assoc 7:e007601 (2018). PubMed: 30371196
- Ma X et al. Interaction of the oncogenic miR-21 microRNA and the p53 tumor suppressor pathway. Carcinogenesis 34:1216-23 (2013). Mouse . PubMed: 23385064
- Kinsella S et al. Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. eNeuro 3:N/A (0). PubMed: 27257617
