PE/Cy7® Anti-VE Cadherin 抗体 [55-7H1] (ab272347)
Key features and details
- PE/Cy7® Mouse monoclonal [55-7H1] to VE Cadherin
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE/Cy7®. Ex: 496nm, Em: 774nm
- Isotype: IgG1
製品の概要
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製品名
PE/Cy7® Anti-VE Cadherin antibody [55-7H1]
VE Cadherin 一次抗体 製品一覧 -
製品の詳細
PE/Cy7® Mouse monoclonal [55-7H1] to VE Cadherin -
由来種
Mouse -
標識
PE/Cy7®. Ex: 496nm, Em: 774nm -
Tested Applications & Species
Application Species Flow Cyt Human -
免疫原
Tissue, cells or virus corresponding to Human VE Cadherin.
Database link: P33151 -
ポジティブ・コントロール
- Flow cyt: HUVEC, HL-60 cells.
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特記事項
This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at +4°C. Do Not Freeze. -
バッファー
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Size exclusion -
特記事項(精製)
Purified from TCS -
ポリ/モノ
モノクローナル -
クローン名
55-7H1 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
アプリケーション
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab272347 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
アプリケーション | Species |
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Flow Cyt |
Human
|
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
|
特記事項 |
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Flow Cyt
Use at an assay dependent concentration. |
ターゲット情報
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機能
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. -
組織特異性
Endothelial tissues and brain. -
配列類似性
Contains 5 cadherin domains. -
翻訳後修飾
Phosphorylated on tyrosine residues by KDR/VEGFR-2. Dephosphorylated by PTPRB. -
細胞内局在
Cell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries. - Information by UniProt
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参照データベース
- Entrez Gene: 1003 Human
- Omim: 601120 Human
- SwissProt: P33151 Human
- Unigene: 76206 Human
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別名
- 7B 4 antibody
- 7B4 antibody
- 7B4 antigen antibody
see all
画像
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Separation of HUVEC cells (Red) from HL-60 (black-dashed) in flow cytometric analysis labeling CD144 using ab272347. (4 μl reagent per milion cells in 100 μl of cell suspension).
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Flow cytometric analysis of HUVEC labeling CD144 with ab272347 at 4μl reagent per milion cells in 100 μl of cell suspension. (4 μl reagent per milion cells in 100 μl of cell suspension).
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab272347 は論文での使用が確認できていません。