PE/Cy7® Anti-PD1 抗体 [EH12.2H7] (ab270681)

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Flow Cytometry - PE/Cy7® Anti-PD1 antibody [EH12.2H7] (ab270681)
  • Flow Cytometry - PE/Cy7® Anti-PD1 antibody [EH12.2H7] (ab270681)

Key features and details

  • PE/Cy7® Mouse monoclonal [EH12.2H7] to PD1
  • Suitable for: Flow Cyt
  • Reacts with: Human
  • Conjugation: PE/Cy7®. Ex: 496nm, Em: 774nm
  • Isotype: IgG1

製品の概要

  • 製品名

    PE/Cy7® Anti-PD1 antibody [EH12.2H7]
    PD1 一次抗体 製品一覧

  • 製品の詳細

    PE/Cy7® Mouse monoclonal [EH12.2H7] to PD1

  • 由来種

    Mouse

  • 標識

    PE/Cy7®. Ex: 496nm, Em: 774nm

  • 特異性

    This antibody recognizes an extracellular epitope of CD279 / PD-1 (programmed cell death 1), a 55 kDa type I transmembrane protein expressed above all during T cell development, on activated T cells, activated B cells, and activated monocytes.

  • Tested Applications & Species

    Application Species
    Flow Cyt
    Human
    See all applications and species data

  • 免疫原

    The details of the immunogen for this antibody are not available.

  • ポジティブ･コントロール

    • Flow Cyt: Human PHA stimulated peripheral blood mononuclear cells.

  • 特記事項

    This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.

製品の特性

アプリケーション

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab270681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

アプリケーション Species
Flow Cyt
Human
アプリケーション Abreviews 特記事項
Flow Cyt
Use 4µl for 106 cells.

The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension.

 
特記事項
Flow Cyt
Use 4µl for 106 cells.

The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension.

 

ターゲット情報

  • 機能

    Possible cell death inducer, in association with other factors.

  • 関連疾患

    Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.

  • 配列類似性

    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

  • 発生段階

    Induced at programmed cell death.

  • 細胞内局在

    Membrane.
  • Information by UniProt

  • 参照データベース

    • 別名

      • CD279 antibody
      • CD279 antigen antibody
      • hPD 1 antibody
      • hPD l antibody
      • hPD-1 antibody
      • hSLE1 antibody
      • PD 1 antibody
      • PD-1 antibody
      • PD1 antibody
      • PDCD 1 antibody
      • PDCD1 antibody
      • PDCD1_HUMAN antibody
      • Programmed cell death 1 antibody
      • Programmed cell death 1 protein antibody
      • Programmed cell death protein 1 antibody
      • Protein PD 1 antibody
      • Protein PD-1 antibody
      • SLEB2 antibody
      • Systemic lupus erythematosus susceptibility 2 antibody
      see all

    画像

    • Flow Cytometry - PE/Cy7® Anti-PD1 antibody [EH12.2H7] (ab270681)
      Flow Cytometry - PE/Cy7® Anti-PD1 antibody [EH12.2H7] (ab270681)

      Flow cytometry analysis of human PHA stimulated peripheral blood mononuclear labeling PD1 (CD279) using ab270681 (Red). Surface staining.

      Control: CD279 negative blood debris (Black). 

    • Flow Cytometry - PE/Cy7® Anti-PD1 antibody [EH12.2H7] (ab270681)
      Flow Cytometry - PE/Cy7® Anti-PD1 antibody [EH12.2H7] (ab270681)

      Flow cytometry analysis of human PHA stimulated peripheral blood mononuclear labeling PD1 (CD279) using ab270681. Surface staining.

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab270681 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab270681 は論文での使用が確認できていません。

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