PE/Cy7® Anti-CD105 抗体 [MEM-226] (ab272352)
Key features and details
- PE/Cy7® Mouse monoclonal [MEM-226] to CD105
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE/Cy7®. Ex: 496nm, Em: 774nm
- Isotype: IgG2a
Related conjugates and formulations
製品の概要
-
製品名
PE/Cy7® Anti-CD105 antibody [MEM-226]
CD105 一次抗体 製品一覧 -
製品の詳細
PE/Cy7® Mouse monoclonal [MEM-226] to CD105 -
由来種
Mouse -
標識
PE/Cy7®. Ex: 496nm, Em: 774nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to CD105. Recombinant Vaccinia virus containing the human CD105 cDNA
-
ポジティブ・コントロール
- Flow cyt: HUVEC, HEK-293 cells.
-
特記事項
This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at +4°C. Store In the Dark. -
バッファー
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
-
精製度
Size exclusion -
特記事項(精製)
Purified from TCS. -
ポリ/モノ
モノクローナル -
クローン名
MEM-226 -
アイソタイプ
IgG2a -
研究分野
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab272352の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use 4µg for 106 cells.
|
特記事項 |
---|
Flow Cyt
Use 4µg for 106 cells. |
ターゲット情報
-
機能
Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. -
組織特異性
Endoglin is restricted to endothelial cells in all tissues except bone marrow. -
関連疾患
Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity. -
細胞内局在
Membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 2022 Human
- Omim: 131195 Human
- SwissProt: P17813 Human
- Unigene: 76753 Human
-
別名
- AI528660 antibody
- AI662476 antibody
- CD 105 antibody
see all
画像
-
Separation of HUVEC cells (Red) from HEK-293 (black-dashed) in flow cytometric analysis labeling CD105 using ab272352. (4 μl reagent per milion cells in 100 μl of cell suspension).
-
Flow cytometric analysis of HUVEC labeling CD105 with ab272352 at 4μl reagent per milion cells in 100 μl of cell suspension.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab272352 は 1 報の論文で使用されています。
- Liang Y et al. Leukemia Inhibitory Factor Facilitates Self-Renewal and Differentiation and Attenuates Oxidative Stress of BMSCs by Activating PI3K/AKT Signaling. Oxid Med Cell Longev 2022:5772509 (2022). PubMed: 36105481