PE Anti-PDGFR alpha 抗体 [APA5] (ab93531)
Key features and details
- PE Rat monoclonal [APA5] to PDGFR alpha
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
Related conjugates and formulations
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
PE Anti-PDGFR alpha antibody [APA5]
PDGFR alpha 一次抗体 製品一覧 -
製品の詳細
PE Rat monoclonal [APA5] to PDGFR alpha -
由来種
Rat -
標識
PE. Ex: 488nm, Em: 575nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant fragment corresponding to Mouse PDGFR alpha. Extracellular domain of PDGFRa and the Fc portion of human IgG1
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ポジティブ・コントロール
- NIH/3T3 cell line
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
APA5 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab93531の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt | (1) |
Use 0.5µg for 105-8 cells.
A final volume of 100 µl is recommended for staining the cell sample.
ab134674 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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特記事項 |
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Flow Cyt
Use 0.5µg for 105-8 cells. A final volume of 100 µl is recommended for staining the cell sample.
ab134674 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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ターゲット情報
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機能
Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity. -
組織特異性
Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue. -
関連疾患
Note=A chromosomal aberration involving PDGFRA is found in some cases of hypereosinophilic syndrome. Interstitial chromosomal deletion del(4)(q12q12) causes the fusion of FIP1L1 and PDGFRA (FIP1L1-PDGFRA). -
配列類似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 18595 Mouse
- SwissProt: P26618 Mouse
- Unigene: 221403 Mouse
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別名
- Alpha-type platelet-derived growth factor receptor antibody
- CD140 antigen-like family member A antibody
- CD140a antibody
see all
画像
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (5)
ab93531 は 5 報の論文で使用されています。
- Kang MJ et al. Inhibition of Hepatic Stellate Cell Activation Suppresses Tumorigenicity of Hepatocellular Carcinoma in Mice. Am J Pathol 191:2219-2230 (2021). PubMed: 34428424
- Boulanger JJ & Messier C Doublecortin in Oligodendrocyte Precursor Cells in the Adult Mouse Brain. Front Neurosci 11:143 (2017). PubMed: 28400715
- Penton CM et al. Muscle side population cells from dystrophic or injured muscle adopt a fibro-adipogenic fate. PLoS One 8:e54553 (2013). ICC/IF ; Mouse . PubMed: 23336007
- Miyawaki T et al. Tlx, an orphan nuclear receptor, regulates cell numbers and astrocyte development in the developing retina. J Neurosci 24:8124-34 (2004). IHC-Fr . PubMed: 15371513
- Takakura N et al. PDGFR alpha expression during mouse embryogenesis: immunolocalization analyzed by whole-mount immunohistostaining using the monoclonal anti-mouse PDGFR alpha antibody APA5. J Histochem Cytochem 45:883-93 (1997). IHC-P . PubMed: 9199674