PE Anti-HLA Class I 抗体 [W6/32] (ab33257)
Key features and details
- PE Mouse monoclonal [W6/32] to HLA Class I
- Suitable for: Flow Cyt
- Reacts with: Cow, Cat, Human, Monkey, Baboon, Cynomolgus monkey, Macaque monkey
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
Related conjugates and formulations
製品の概要
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製品名
PE Anti-HLA Class I antibody [W6/32]
HLA Class I 一次抗体 製品一覧 -
製品の詳細
PE Mouse monoclonal [W6/32] to HLA Class I -
由来種
Mouse -
標識
PE. Ex: 488nm, Em: 575nm -
特異性
This antibody recognises an antigenic determinant shared among products of the HLA A, B and C loci. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Cow, Cat, Human, Monkey, Baboon, Cynomolgus monkey, Macaque monkey -
免疫原
Tissue, cells or virus corresponding to Human HLA Class I. Purified human tonsil lymphocyte membranes.
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ポジティブ･コントロール
- Human peripheral blood lymphocytes.
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特記事項
50 tests will be supplied typically at a volume of 0.5ml at a concentration of 0.1mg/ml (concentration prior to conjugation).The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
This antibody was purified from tissue culture supernatant. -
ポリ/モノ
モノクローナル -
クローン名
W6/32 -
ミエローマ
NS1/1-Ag4-1 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab33257の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use 10µl for 106 cells.
ab91363 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. Use 10µl to label 106 cells or 100µl whole blood. |
| 特記事項 |
|---|
|
Flow Cyt
Use 10µl for 106 cells. ab91363 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. Use 10µl to label 106 cells or 100µl whole blood. |
ターゲット情報
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関連性
HLA CLass I is involved in the presentation of foreign antigens to the immune system. -
細胞内局在
Plasma membrane -
参照データベース
- Entrez Gene: 3105 Human
- Entrez Gene: 3133 Human
- Entrez Gene: 3134 Human
- Entrez Gene: 3135 Human
- Omim: 142800 Human
- SwissProt: O15506 Human
- SwissProt: P04439 Human
- SwissProt: Q5MCQ6 Human
see all -
別名
- DKFZp686P19218 antibody
- EA1.2 antibody
- EA2.1 antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (8)
ab33257 は 8 報の論文で使用されています。
- Chen HC et al. Induction of metastatic cancer stem cells from the NK/LAK-resistant floating, but not adherent, subset of the UP-LN1 carcinoma cell line by IFN-?. Lab Invest 91:1502-13 (2011). PubMed: 21691263
- Hurton LV et al. Identifying candidate allogeneic NK-cell donors for hematopoietic stem-cell transplantation based on functional phenotype. Leukemia 24:1059-62 (2010). PubMed: 20164852
- Daniel D et al. Pathway of apoptosis induced in Jurkat T lymphoblasts by anti-HLA class I antibodies. Hum Immunol 65:189-99 (2004). PubMed: 15041157
- Andratschke M et al. MHC-class I antigen expression on micrometastases in bone marrow of patients with head and neck squamous cell cancer. Anticancer Res 23:1467-71 (2003). PubMed: 12820411
- Cabrera CM et al. Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: beta2-microglobulin inactivation in MSI-positive tumors and LMP7/TAP2 downregulation in MSI-negative tumors. Tissue Antigens 61:211-9 (2003). PubMed: 12694570
- Jaramillo A et al. Anti-HLA class I antibody binding to airway epithelial cells induces production of fibrogenic growth factors and apoptotic cell death: a possible mechanism for bronchiolitis obliterans syndrome. Hum Immunol 64:521-9 (2003). PubMed: 12691702
- Wu T et al. Detection of soluble HLA class I antigens by ELISA and determination of its reference value in population of Guangdong province. Di Yi Jun Yi Da Xue Xue Bao 22:931-3 (2002). PubMed: 12377624
- Pangault C et al. Lung macrophages and dendritic cells express HLA-G molecules in pulmonary diseases. Hum Immunol 63:83-90 (2002). PubMed: 11821155
