PE Anti-CD38 抗体 [FS02] (ab1174)
Key features and details
- PE Mouse monoclonal [FS02] to CD38
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
製品の概要
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製品名
PE Anti-CD38 antibody [FS02]
CD38 一次抗体 製品一覧 -
製品の詳細
PE Mouse monoclonal [FS02] to CD38 -
由来種
Mouse -
標識
PE. Ex: 488nm, Em: 575nm -
特異性
This antibody reacts with a type II membrane glycopeptide with a transmembrane sequence near the NH2-terminus. -
種交差性
交差種: Human -
特記事項
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
Preservative: 0.1% Sodium azide
Constituent: 0.5% BSA -
Concentration information loading... -
ポリ/モノ
モノクローナル -
クローン名
FS02 -
ミエローマ
unknown -
アイソタイプ
IgG1 -
軽鎖の種類
unknown -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
CD38 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.
10µl ofCD38 (PE) is sufficient for labelling of 1x106 cells.
ターゲット情報
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機能
Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. -
組織特異性
Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. -
配列類似性
Belongs to the ADP-ribosyl cyclase family. -
発生段階
Preferentially expressed at both early and late stages of the B and T-cell maturation. It is also detected on erythroid and myeloid progenitors in bone marrow, where the level of surface expression was shown to decrease during differentiation of blast-forming unit E to colony-forming unit E. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 952 Human
- Omim: 107270 Human
- SwissProt: P28907 Human
- Unigene: 479214 Human
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製品の状態
There are 2 isoforms produced by alternative splicing. -
別名
- Acute lymphoblastic leukemia cells antigen CD38 antibody
- ADP ribosyl cyclase 1 antibody
- ADP ribosyl cyclase antibody
see all
参考文献 (4)
ab1174 は 4 報の論文で使用されています。
- Wen HJ et al. Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis. Cell Mol Gastroenterol Hepatol 8:173-192 (2019). PubMed: 31125624
- Ramírez T et al. Prevention of aneuploidy by S-adenosyl-methionine in human cells treated with sodium arsenite. Mutat Res 617:16-22 (2007). PubMed: 17241646
- Morra M et al. CD38 is functionally dependent on the TCR/CD3 complex in human T cells. FASEB J 12:581-92 (1998). PubMed: 9576485
- Zupo S et al. CD38 signaling by agonistic monoclonal antibody prevents apoptosis of human germinal center B cells. Eur J Immunol 24:1218-22 (1994). PubMed: 8181532
