PE Anti-CD103 抗体 [OX62] (ab95763)
Key features and details
- PE Mouse monoclonal [OX62] to CD103
- Suitable for: Flow Cyt
- Reacts with: Rat
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
製品の概要
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製品名
PE Anti-CD103 antibody [OX62]
CD103 一次抗体 製品一覧 -
製品の詳細
PE Mouse monoclonal [OX62] to CD103 -
由来種
Mouse -
標識
PE. Ex: 488nm, Em: 575nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Rat -
免疫原
Tissue, cells or virus. Density gradient enriched PVG Rat thoracic duct dendritic cells.
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ポジティブ・コントロール
- Rat splenocytes.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
OX62 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95763の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt |
Use 0.125-0.25µg for 105 cells.
Cell number should be determined empirically but can range from 105 to 108 cells/test (based on a test volume of 100 µl).
ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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特記事項 |
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Flow Cyt
Use 0.125-0.25µg for 105 cells. Cell number should be determined empirically but can range from 105 to 108 cells/test (based on a test volume of 100 µl).
ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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ターゲット情報
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機能
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. -
組織特異性
Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. -
配列類似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
ドメイン
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
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別名
- A530055J10 antibody
- alpha-E1 antibody
- alpha-M290 antibody
see all
画像
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Flow cytometry staining of rat splenocytes with Anti-Rat CD4 FITC and 0.125 µg of Mouse IgG1 ? Isotype Control PE (left) or 0.125 µg of ab95763 (right). Cells in the lymphocyte gate were used for analysis and events are displayed after gating out CD3+ T cells and CD45RB+ cells and gating on the remaining cells, which are MHC Class II+.
データシートおよび資料
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Datasheet download
参考文献 (4)
ab95763 は 4 報の論文で使用されています。
- Watanabe H et al. Adipose-derived mesenchymal stem cells attenuate rejection in a rat lung transplantation model. J Surg Res 227:17-27 (2018). IHC-P . PubMed: 29804850
- Hubert FX et al. Rat plasmacytoid dendritic cells are an abundant subset of MHC class II+ CD4+CD11b-OX62- and type I IFN-producing cells that exhibit selective expression of Toll-like receptors 7 and 9 and strong responsiveness to CpG. J Immunol 172:7485-94 (2004). PubMed: 15187127
- Voisine C et al. Two phenotypically distinct subsets of spleen dendritic cells in rats exhibit different cytokine production and T cell stimulatory activity. J Immunol 169:2284-91 (2002). PubMed: 12193693
- Brenan M & Puklavec M The MRC OX-62 antigen: a useful marker in the purification of rat veiled cells with the biochemical properties of an integrin. J Exp Med 175:1457-65 (1992). Flow Cyt . PubMed: 1588275