PE Anti-CD10 抗体 [FR4D11/F3] (ab1165)
Key features and details
- PE Mouse monoclonal [FR4D11/F3] to CD10
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
製品の概要
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製品名
PE Anti-CD10 antibody [FR4D11/F3]
CD10 一次抗体 製品一覧 -
製品の詳細
PE Mouse monoclonal [FR4D11/F3] to CD10 -
由来種
Mouse -
標識
PE. Ex: 488nm, Em: 575nm -
種交差性
交差種: Human -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
Preservative: 0.1% Sodium azide
Constituent: 0.5% BSA -
Concentration information loading... -
ポリ/モノ
モノクローナル -
クローン名
FR4D11/F3 -
ミエローマ
unknown -
アイソタイプ
IgG1 -
軽鎖の種類
unknown -
研究分野
関連製品
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Isotype control
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Recombinant Protein
アプリケーション
追加情報
Characterization of leukaemias and lymphomas in human lysed whole peripheral blood or mononuclear cells separated by density gradient.
Childhood ALL prognosis (patients CD10+ have a better prognosis than CD10-).
CD10 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.
10µl ofCD10 (PE) is sufficient for labelling of 1x106 cells.
Molecular F/P ratio: 1.0
Childhood ALL prognosis (patients CD10+ have a better prognosis than CD10-).
CD10 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.
10µl ofCD10 (PE) is sufficient for labelling of 1x106 cells.
Molecular F/P ratio: 1.0
ターゲット情報
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機能
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. -
配列類似性
Belongs to the peptidase M13 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 4311 Human
- Omim: 120520 Human
- SwissProt: P08473 Human
- Unigene: 307734 Human
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別名
- Atriopeptidase antibody
- CALLA antibody
- CD10 antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab1165 は 2 報の論文で使用されています。
- Husak Z & Dworzak MN CD99 ligation upregulates HSP70 on acute lymphoblastic leukemia cells and concomitantly increases NK cytotoxicity. Cell Death Dis 3:e425 (2012). Flow Cyt ; Human . PubMed: 23152061
- Ferletta M et al. Canine mammary tumors contain cancer stem-like cells and form spheroids with an embryonic stem cell signature. Int J Dev Biol 55:791-9 (2011). PubMed: 22161835