Anti-PDCD2 抗体 [EPR7158] (ab133324)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7158] to PDCD2
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-PDCD2 antibody [EPR7158]
PDCD2 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR7158] to PDCD2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF or IHC-P -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- 293T, HeLa, and Ramos cell lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
解離定数(KD 値)
KD = 1.06 x 10 -10 M Learn more about KD -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
EPR7158 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab133324の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/1000 - 1/10000. Predicted molecular weight: 39 kDa.
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特記事項 |
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WB
1/1000 - 1/10000. Predicted molecular weight: 39 kDa. |
ターゲット情報
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機能
May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation. -
組織特異性
Ubiquitous. -
配列類似性
Contains 1 MYND-type zinc finger. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 5134 Human
- Entrez Gene: 18567 Mouse
- Entrez Gene: 58934 Rat
- Omim: 600866 Human
- SwissProt: Q16342 Human
- SwissProt: P46718 Mouse
- SwissProt: P47816 Rat
- Unigene: 367900 Human
see all -
別名
- MGC12347 antibody
- OTTHUMP00000017702 antibody
- PDCD 2 antibody
see all
画像
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All lanes : Anti-PDCD2 antibody [EPR7158] (ab133324) at 1/1000 dilution
Lane 1 : 293T cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : Ramos cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 39 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab133324 は 4 報の論文で使用されています。
- He F et al. Effect of tumor-associated macrophages on lncRNA PURPL/miR-363/PDZD2 axis in osteosarcoma cells. Cell Death Discov 7:307 (2021). PubMed: 34686652
- Landry-Voyer AM et al. PDCD2 functions as an evolutionarily conserved chaperone dedicated for the 40S ribosomal protein uS5 (RPS2). Nucleic Acids Res 48:12900-12916 (2020). PubMed: 33245768
- Liu H et al. PDCD2 sensitizes HepG2 cells to sorafenib by suppressing epithelial-mesenchymal transition. Mol Med Rep 19:2173-2179 (2019). PubMed: 30664177
- Santra T et al. An Integrated Global Analysis of Compartmentalized HRAS Signaling. Cell Rep 26:3100-3115.e7 (2019). PubMed: 30865897