製品名PD-L1 Antibody Panel (28-8, 73-10, SP142, CAL10)
PD-L1 キット 製品一覧
PD-L1 Antibody Panel ab239749 is a panel of 4 recombinant rabbit monoclonal antibodies against human PD-L1. They are provided in small sizes to allow you to easily evaluate which is the best PD-L1 antibody for your human PD-L1 research assay needs.
For guidelines on how to use each antibody within the panel, please consult the individual datasheet for each antibody.
- Rabbit monoclonal [73-10] to PD-L1 (10 ul) ab228415
- Rabbit monoclonal [28-8] to PD-L1 (10 ul) ab205921
- Rabbit monoclonal [SP142] to PD-L1 (25 ul) ab228462
- Rabbit monoclonal [CAL10] to PD-L1 (10 ul) ab237726
See our comparison table of PD-L1 clones 28-8, 73-10, SP142 and CAL10 to help you find the optimal recombinant monoclonal PD-L1 antibody clone for your research.
All of the antibodies are ideal for use with immunohistochemistry with paraffin-embedded / formalin-fixed sections (as well as with other techniques).
保存方法Store at -20°C. Please refer to protocols.
内容 1 kit ab205921 - Anti-PD-L1 antibody [28-8] 1 x 10µl ab228415 - Anti-PD-L1 antibody [73-10] 1 x 10µl ab237726 - Anti-PD-L1 antibody [CAL10] 1 x 10µl ab228462 - Anti-PD-L1 antibody [SP142] - C-terminal 1 x 25µl
機能Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
組織特異性Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.
配列類似性Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
細胞内局在Cell membrane and Endomembrane system.
- Information by UniProt
- B7 H
- B7 H1
- B7 homolog 1
Formalin-fixed, paraffin-embedded NSCLC (Non-small-cell lung carcinoma) tissue stained for PD-L1 using CAL10 at 0.3 µg/ml dilution in immunohistochemical analysis. Positive staining (Left panel) and negative staining (Right panel).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of lung cancer tissue samples. Comparing the staining of PD-L1 with different monoclonal antibodies. ab228415 (73-10) showed higher sensitivity to PD-L1 compared to the other clones.
Image taken from the Blueprint study - Tsao 2018
ab239749 has not yet been referenced specifically in any publications.