Anti-Parathyroid Hormone 抗体 [B1/70] (ab14496)
Key features and details
- Mouse monoclonal [B1/70] to Parathyroid Hormone
- Suitable for: IHC-Fr, ELISA, IHC-P, RIA
- Reacts with: Human
- Isotype: IgG1
製品の概要
-
製品名
Anti-Parathyroid Hormone antibody [B1/70]
Parathyroid Hormone 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [B1/70] to Parathyroid Hormone -
由来種
Mouse -
特異性
Ab14496 reacts with parathyroid hormone peptides:aa 15-25; 1-34; 1-38; 1-84; 7-84. There are no cross reactivities with parathyroid hormone peptides: aa 1-3; 1-10; 4-16; 28-48; 39-84; 44-68; 53-84; PTHrP aa 1- 86. -
アプリケーション
適用あり: IHC-Fr, ELISA, IHC-P, RIAmore details -
種交差性
交差種: Human
交差が予測される動物種: Horse, Cow, Cat, Dog, Pig, Macaque monkey
-
免疫原
Poly Lysin conjugated synthetic peptide:
SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFVALG
, corresponding to amino acids 1-38 of Human Parathyroid Hormone. -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.05% Sodium azide
Constituent: 0.605% Tris -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
B1/70 -
アイソタイプ
IgG1 -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab14496の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-Fr | ||
| ELISA | ||
| IHC-P | ||
| RIA |
| 特記事項 |
|---|
IHC-P: Use at a concentration of 2 µg/ml.
IHC-Fr: Use at a concentration of 2 µg/ml.
RIA: Use at a concentration of 25 ng/ml.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
-
機能
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. -
関連疾患
Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. -
配列類似性
Belongs to the parathyroid hormone family. -
細胞内局在
Secreted. - Information by UniProt
-
参照データベース
- Entrez Gene: 280903 Cow
- Entrez Gene: 403986 Dog
- Entrez Gene: 5741 Human
- Entrez Gene: 399502 Pig
- Omim: 168450 Human
- SwissProt: P01268 Cow
- SwissProt: P52212 Dog
- SwissProt: P01270 Human
see all -
別名
- hPTH antibody
- Parathormone antibody
- Parathyrin antibody
see all
データシートおよび資料
-
Datasheet download
参考文献 (0)
ab14496 は論文での使用が確認できていません。
