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ab8805 は 87 報の論文で使用されています。

  • Abou-Antoun TJ  et al. Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant properties: A possible explanation for radio-therapy resistance. PLoS One 13:e0189711 (2018). PubMed: 29298329
  • Jia J  et al. Fibroblast activation protein-a promotes the growth and migration of lung cancer cells via the PI3K and sonic hedgehog pathways. Int J Mol Med 41:275-283 (2018). PubMed: 29115573
  • Lu Y  et al. Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs. Mol Ther Nucleic Acids 10:349-360 (2018). WB . PubMed: 29499946
  • Zhang B  et al. Metastasis-associated protein 2 promotes the metastasis of non-small cell lung carcinoma by regulating the ERK/AKT and VEGF signaling pathways. Mol Med Rep 17:4899-4908 (2018). PubMed: 29393472
  • Qian YY  et al. Pterostilbene increases PTEN expression through the targeted downregulation of microRNA-19a in hepatocellular carcinoma. Mol Med Rep 17:5193-5201 (2018). PubMed: 29393488
  • Guo J  et al. Androgen receptor reverts dexamethasone-induced inhibition of prostate cancer cell proliferation and migration. Mol Med Rep 17:5887-5893 (2018). PubMed: 29436611
  • Zhang J & Li Z ß-inducible gene-h3 promotes human breast carcinoma cell metastasis by activating the phosphatidylinositol 3-kinase/protein kinase B signaling pathway. Exp Ther Med 15:2910-2916 (2018). PubMed: 29599830
  • Pi Z  et al. Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery. Mol Med Rep 17:6497-6505 (2018). PubMed: 29488606
  • Wang L  et al. TIPE-2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3-kinase/AKT signaling pathway. Mol Med Rep 17:7017-7026 (2018). PubMed: 29568863
  • Du L  et al. Everolimus inhibits breast cancer cell growth through PI3K/AKT/mTOR signaling pathway. Mol Med Rep 17:7163-7169 (2018). PubMed: 29568883
  • Zhang M  et al. Semen Cassiae Extract Improves Glucose Metabolism by Promoting GlUT4 Translocation in the Skeletal Muscle of Diabetic Rats. Front Pharmacol 9:235 (2018). PubMed: 29670524
  • Zhang Q  et al. PPAR? Antagonizes Hypoxia-Induced Activation of Hepatic Stellate Cell through Cross Mediating PI3K/AKT and cGMP/PKG Signaling. PPAR Res 2018:6970407 (2018). PubMed: 29686697
  • Wang X  et al. Secretory Clusterin Mediates Oxaliplatin Resistance via the Gadd45a/PI3K/Akt Signaling Pathway in Hepatocellular Carcinoma. J Cancer 9:1403-1413 (2018). PubMed: 29721050
  • Zhang C & Zhang J Decreased expression of microRNA-223 promotes cell proliferation in hepatocellular carcinoma cells via the insulin-like growth factor-1 signaling pathway. Exp Ther Med 15:4325-4331 (2018). PubMed: 29725374
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  • Wang X  et al. Costus root granules improve ulcerative colitis through regulation of TGF-ß mediation of the PI3K/AKT signaling pathway. Exp Ther Med 15:4477-4484 (2018). PubMed: 29731832
  • Wang Z  et al. Long noncoding RNA maternally expressed gene 3 knockdown alleviates lipopolysaccharide-induced inflammatory injury by up-regulation of miR-203 in ATDC5 cells. Biomed Pharmacother 100:240-249 (2018). WB . PubMed: 29432995
  • Zhou S  et al. Low expression of SEMA6C accelerates the primordial follicle activation in the neonatal mouse ovary. J Cell Mol Med 22:486-496 (2018). WB ; Mouse . PubMed: 28881413
  • Hou GR  et al. Juglanin ameliorates UVB-induced skin carcinogenesis via anti-inflammatory and proapoptotic effects in vivo and in vitro. Int J Mol Med 42:41-52 (2018). PubMed: 29620254
  • Qi Z  et al. Pegylated liposomal-paclitaxel induces ovarian cancer cell apoptosis via TNF-induced ERK/AKT signaling pathway. Mol Med Rep 17:7497-7504 (2018). PubMed: 29620264
  • Ying Y & Luo J Salidroside promotes human periodontal ligament cell proliferation and osteocalcin secretion via ERK1/2 and PI3K/Akt signaling pathways. Exp Ther Med 15:5041-5045 (2018). PubMed: 29805528
  • Zhang DD  et al. Vildagliptin, a DPP4 inhibitor, alleviates diabetes-associated cognitive deficits by decreasing the levels of apoptosis-related proteins in the rat hippocampus. Exp Ther Med 15:5100-5106 (2018). PubMed: 29805536
  • Zhang Y  et al. PRL-3 promotes gastric cancer peritoneal metastasis via the PI3K/AKT signaling pathway in vitro and in vivo. Oncol Lett 15:9069-9074 (2018). PubMed: 29805638
  • Gu HJ & Zhou B Focal adhesion kinase promotes progression and predicts poor clinical outcomes in patients with osteosarcoma. Oncol Lett 15:6225-6232 (2018). PubMed: 29849782
  • Xie C  et al. N-Acetylcysteine Reduces ROS-Mediated Oxidative DNA Damage and PI3K/Akt Pathway Activation Induced by Helicobacter pylori Infection. Oxid Med Cell Longev 2018:1874985 (2018). PubMed: 29854076
  • Dai C  et al. MiR-206 inhibits epithelial ovarian cancer cells growth and invasion via blocking c-Met/AKT/mTOR signaling pathway. Biomed Pharmacother 104:763-770 (2018). WB ; Human . PubMed: 29807226
  • Zhang B  et al. Hypoxia-inducible factor-1 promotes cancer progression through activating AKT/Cyclin D1 signaling pathway in osteosarcoma. Biomed Pharmacother 105:1-9 (2018). WB . PubMed: 29807229
  • Xu Y  et al. Long non-coding RNA TUG1 protects renal tubular epithelial cells against injury induced by lipopolysaccharide via regulating microRNA-223. Biomed Pharmacother 104:509-519 (2018). WB . PubMed: 29800915
  • Yan R  et al. Salidroside protects hypoxia-induced injury by up-regulation of miR-210 in rat neural stem cells. Biomed Pharmacother 103:1490-1497 (2018). WB ; Rat . PubMed: 29864934
  • Li J  et al. Down-regulation of microRNA-27b promotes retinal pigment epithelial cell proliferation and migration by targeting Nox2. Pathol Res Pract 214:925-933 (2018). WB ; Human . PubMed: 29858119
  • Liu QY  et al. Inflammation responses in patients with pulmonary tuberculosis in an intensive care unit. Exp Ther Med 15:2719-2726 (2018). PubMed: 29456674
  • Yang R  et al. Knockout of the placenta specific 8 gene radiosensitizes nasopharyngeal carcinoma cells by activating the PI3K/AKT/GSK3ß pathway. Am J Transl Res 10:455-464 (2018). PubMed: 29511439
  • Lu H  et al. Decreased phosphorylation of PDGFR-ß impairs the angiogenic potential of expanded endothelial progenitor cells via the inhibition of PI3K/Akt signaling. Int J Mol Med 39:1492-1504 (2017). WB ; Human . PubMed: 28487975
  • Zhang D  et al. Fibulin-4 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition via the PI3K/Akt/mTOR pathway. Int J Oncol 50:1513-1530 (2017). WB ; Human . PubMed: 28339091
  • Zhao Y  et al. a2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/ß-catenin pathway. Oncogenesis 6:e343 (2017). PubMed: 28553930
  • Zheng Y  et al. The extracellular vesicles secreted by lung cancer cells in radiation therapy promote endothelial cell angiogenesis by transferring miR-23a. PeerJ 5:e3627 (2017). WB ; Human . PubMed: 28852584
  • Luo J  et al. Ursolic acid inhibits breast cancer growth by inhibiting proliferation, inducing autophagy and apoptosis, and suppressing inflammatory responses via the PI3K/AKT and NF-?B signaling pathwaysin vitro. Exp Ther Med 14:3623-3631 (2017). PubMed: 29042957
  • You ML  et al. Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent. Oncotarget 8:39323-39344 (2017). PubMed: 28445151
  • Song B  et al. Beclin 1 overexpression inhibits chondrocyte apoptosis and downregulates extracellular matrix metabolism in osteoarthritis. Mol Med Rep 16:3958-3964 (2017). PubMed: 28731147
  • Yang L  et al. The role of mTOR signaling pathway on cognitive functions in cerebral ischemia-reperfusion. Exp Ther Med 14:2839-2844 (2017). PubMed: 28912846
  • Zhang W  et al. LKB1 loss cooperating with BRAF V600E promotes melanoma cell invasion and migration by up-regulation MMP-2 via PI3K/Akt/mTOR pathway. Oncotarget 8:113847-113857 (2017). PubMed: 29371951
  • Feng F  et al. Hoxa5 increases mitochondrial apoptosis by inhibiting Akt/mTORC1/S6K1 pathway in mice white adipocytes. Oncotarget 8:95332-95345 (2017). PubMed: 29221131
  • Chen Z  et al. LYTAK1 attenuates proliferation of retinal pigment epithelial cells through TGF-ß-mediated epithelial-mesenchymal transition via the ERK/AKT signaling pathway. Exp Ther Med 14:4951-4957 (2017). PubMed: 29201199
  • Huang XY  et al. Missing-in-metastasis B (MIM-B) combined with caveolin-1 promotes metastasis of hepatocellular carcinoma. Oncotarget 8:95450-95465 (2017). PubMed: 29221140
  • Li L  et al. Expression of the ß3 subunit of Na+/K+-ATPase is increased in gastric cancer and regulates gastric cancer cell progression and prognosis via the PI3/AKT pathway. Oncotarget 8:84285-84299 (2017). PubMed: 29137423
  • Shinsuke K  et al. Chronic irradiation with low-dose-rate 137Cs-? rays inhibits NGF-induced neurite extension of PC12 cells via Ca2+/calmodulin-dependent kinase II activation. J Radiat Res 58:809-815 (2017). PubMed: 29106600
  • Chong QY  et al. Release of HER2 repression of trefoil factor 3 (TFF3) expression mediates trastuzumab resistance in HER2+/ER+ mammary carcinoma. Oncotarget 8:74188-74208 (2017). PubMed: 29088778
  • Yu J  et al. miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway. Med Sci Monit 23:71-77 (2017). PubMed: 28057912
  • Yu N  et al. Anti-Diabetic Effects of Jiang Tang Xiao Ke Granule via PI3K/Akt Signalling Pathway in Type 2 Diabetes KKAy Mice. PLoS One 12:e0168980 (2017). Mouse . PubMed: 28045971
  • Zhang Y  et al. Effect of Tetramethylpyrazine on Atherosclerosis and SCAP/SREBP-1c Signaling Pathway in ApoE(-/-) Mice Fed with a High-Fat Diet. Evid Based Complement Alternat Med 2017:3121989 (2017). WB ; Mouse . PubMed: 28491104
  • Gao Q  et al. Arsenic trioxide inhibits tumor-induced myeloid-derived suppressor cells and enhances T-cell activity. Oncol Lett 13:2141-2150 (2017). WB ; Mouse . PubMed: 28454374
  • Chen Y  et al. Proliferation and invasion of ovarian cancer cells are suppressed by knockdown of TRIM11. Oncol Lett 14:2125-2130 (2017). PubMed: 28781653
  • Deng YP  et al. Human bocavirus induces apoptosis and autophagy in human bronchial epithelial cells. Exp Ther Med 14:753-758 (2017). PubMed: 28672995
  • Hu J  et al. Tumor grade related expression of neuroglobin is negatively regulated by PPAR? and confers antioxidant activity in glioma progression. Redox Biol 12:682-689 (2017). WB . PubMed: 28410531
  • Jiang G  et al. Mediation of insulin growth factor-1 in Alzheimer's disease and the mechanism of PRNP genetic expression and the PI3K/Akt signaling pathway. Exp Ther Med 13:2763-2766 (2017). WB . PubMed: 28587338
  • Su W  et al. GABARAPL1 suppresses metastasis by counteracting PI3K/Akt pathway in prostate cancer. Oncotarget 8:4449-4459 (2017). PubMed: 27966458
  • Liu Z  et al. Detection of microRNA-200b may predict the inhibitory effect of gefitinib on non-small cell lung cancer and its potential mechanism. Oncol Lett 12:5349-5355 (2016). PubMed: 28101246
  • Liu Z  et al. Adiponectin reduces ER stress-induced apoptosis through PPARa transcriptional regulation of ATF2 in mouse adipose. Cell Death Dis 7:e2487 (2016). WB ; Mouse . PubMed: 27882945
  • Yang R  et al. Neutrophil elastase enhances the proliferation and decreases apoptosis of leukemia cells via activation of PI3K/Akt signaling. Mol Med Rep 13:4175-82 (2016). WB ; Human . PubMed: 27035679
  • Lu H  et al. Transient hypoxia reprograms differentiating adipocytes for enhanced insulin sensitivity and triglyceride accumulation. Int J Obes (Lond) 40:121-8 (2016). Mouse . PubMed: 26219415
  • Liang Q  et al. Application of citrate as a tricarboxylic acid (TCA) cycle intermediate, prevents diabetic-induced heart damages in mice. Iran J Basic Med Sci 19:43-8 (2016). WB ; Mouse . PubMed: 27096063
  • Tu M  et al. MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes. Sci Rep 6:25032 (2016). WB ; Human . PubMed: 27126955
  • Lv B  et al. Activated Microglia Induce Bone Marrow Mesenchymal Stem Cells to Produce Glial Cell-Derived Neurotrophic Factor and Protect Neurons Against Oxygen-Glucose Deprivation Injury. Front Cell Neurosci 10:283 (2016). PubMed: 28018176
  • Li T  et al. Wen-Xin Decoction ameliorates vascular endothelium dysfunction via the PI3K/AKT/eNOS pathway in experimental atherosclerosis in rats. BMC Complement Altern Med 16:27 (2016). Rat . PubMed: 26803585
  • Li XJ  et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-?B signaling pathways in osteoprotegerin knockout mice. Int J Mol Med N/A:N/A (2016). WB ; Mouse . PubMed: 27840967
  • Qian CJ  et al. Notch4 inhibition reduces migration and invasion and enhances sensitivity to docetaxel by inhibiting Akt/fascin in pancreatic cancer cells. Oncol Lett 12:3499-3505 (2016). WB ; Human . PubMed: 27900027
  • Bauer J  et al. Activin and TGFß use diverging mitogenic signaling in advanced colon cancer. Mol Cancer 14:182 (2015). WB ; Human . PubMed: 26497569
  • Xu S  et al. Downregulation of long noncoding RNA MALAT1 induces epithelial-to-mesenchymal transition via the PI3K-AKT pathway in breast cancer. Int J Clin Exp Pathol 8:4881-91 (2015). WB ; Human . PubMed: 26191181
  • Vishwamitra D  et al. The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK? T-cell lymphoma. Mol Cancer 14:53 (2015). PubMed: 25884514
  • Yang Z  et al. Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway. Oncotarget 6:31916-26 (2015). IHC-P ; Human . PubMed: 26376616
  • Chang X  et al. Orexin-A stimulates 3ß-hydroxysteroid dehydrogenase expression and cortisol production in H295R human adrenocortical cells through the AKT pathway. Int J Mol Med 34:1523-8 (2014). Human . PubMed: 25319929
  • Yu HC  et al. Erlotinib derivative inhibits hepatocellular carcinoma by targeting CIP2A to reactivate protein phosphatase 2A. Cell Death Dis 5:e1359 (2014). IHC-P . PubMed: 25077545
  • Bai X  et al. Antiangiogenic treatment diminishes renal injury and dysfunction via regulation of local AKT in early experimental diabetes. PLoS One 9:e96117 (2014). IHC-FoFr, IHC-Fr ; Rat . PubMed: 24759991
  • Liao HF  et al. DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells. Development 141:2402-13 (2014). PubMed: 24850856
  • Peng YF  et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy 9:2056-68 (2013). WB ; Human . PubMed: 24157892
  • Chase A  et al. Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements. Haematologica 98:404-8 (2013). WB ; Mouse . PubMed: 22875628
  • Liu Y  et al. The role of phospholipase D in modulating the MTOR signaling pathway in polycystic kidney disease. PLoS One 8:e73173 (2013). PubMed: 24009738
  • Obradovic M  et al. Estradiol In Vivo Induces Changes in Cardiomyocytes Size in Obese Rats. Angiology N/A:N/A (2013). Rat . PubMed: 24327768
  • Manetti M  et al. Overexpression of VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, leads to insufficient angiogenesis in patients with systemic sclerosis. Circ Res 109:e14-26 (2011). Human . PubMed: 21636803
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  • Han JW  et al. Impaired PI3K/Akt signal pathway and hepatocellular injury in high-fat fed rats. World J Gastroenterol 16:6111-8 (2010). WB ; Rat . PubMed: 21182226
  • Rabbani SA  et al. An anti-urokinase plasminogen activator receptor antibody (ATN-658) blocks prostate cancer invasion, migration, growth, and experimental skeletal metastasis in vitro and in vivo. Neoplasia 12:778-88 (2010). IHC-P ; Human . PubMed: 20927316
  • Nakou M  et al. Gene network analysis of bone marrow mononuclear cells reveals activation of multiple kinase pathways in human systemic lupus erythematosus. PLoS One 5:e13351 (2010). WB ; Mouse . PubMed: 20976278
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