Anti-p75 NGF Receptor 抗体 [NGFR5] - BSA and Azide free (ab212682)
Key features and details
- Mouse monoclonal [NGFR5] to p75 NGF Receptor - BSA and Azide free
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
Anti-p75 NGF Receptor antibody [NGFR5] - BSA and Azide free
p75 NGF Receptor 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [NGFR5] to p75 NGF Receptor - BSA and Azide free -
由来種
Mouse -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
非交差種: Mouse, Rat -
免疫原
Tissue, cells or virus corresponding to Human p75 NGF Receptor. Immunogen from p75 NGF Receptor from A875 melanoma cells.
Database link: P08138 -
エピトープ
Epitope spans aa 1-160 of the extracellular domain of NGFR/NTR. -
ポジティブ・コントロール
- Neuronal axons, Schwann cells, and perineural cells of peripheral nerves, or tumors of nerve sheath differentiation e.g. Schwannoma, Neurofibroma. Soma and axons of sensory neurons, and ganglionic satellite cells. Melanomas.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Constituent: 100% PBS -
キャリア・フリー
はい -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
Purified from bioreactor concentrate. -
ポリ/モノ
モノクローナル -
クローン名
NGFR5 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Conjugation kits
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab212682の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
for 30 minutes at room temperature. |
特記事項 |
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IHC-P
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. for 30 minutes at room temperature. |
ターゲット情報
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機能
Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. -
配列類似性
Contains 1 death domain.
Contains 4 TNFR-Cys repeats. -
ドメイン
Death domain is responsible for interaction with RANBP9.
The extracellular domain is responsible for interaction with NTRK1. -
翻訳後修飾
N- and O-glycosylated.
O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc.
Phosphorylated on serine residues. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 4804 Human
- Omim: 162010 Human
- SwissProt: P08138 Human
- Unigene: 415768 Human
- Unigene: 681726 Human
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別名
- CD271 antibody
- CD271 antigen antibody
- Gp80 LNGFR antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (0)
ab212682 は論文での使用が確認できていません。