Anti-P2Y13 抗体 [EPR3698] (ab108444)
![Western blot - Anti-P2Y13 antibody [EPR3698] (ab108444)](https://www.abcam.co.jp/ps/products/108/ab108444/Images/ab108444-121177-anti-p2y13-antibody-epr3698-western-blot.jpg "Western blot - Anti-P2Y13 antibody [EPR3698] (ab108444)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR3698] to P2Y13
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-P2Y13 antibody [EPR3698]
P2Y13 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR3698] to P2Y13 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC,IHC-P or IP -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- Human spleen tissue lysate, HeLa cell lysate, HepG2 cell lysate, Jurkat cell lysate.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading... -
精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
EPR3698 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab108444の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000 - 1/5000. Predicted molecular weight: 41 kDa.
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| 特記事項 |
|---|
|
WB
1/1000 - 1/5000. Predicted molecular weight: 41 kDa. |
追加情報
Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
ターゲット情報
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機能
Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. -
組織特異性
Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 53829 Human
- Entrez Gene: 74191 Mouse
- Entrez Gene: 310444 Rat
- Omim: 606380 Human
- SwissProt: Q9BPV8 Human
- SwissProt: Q9D8I2 Mouse
- SwissProt: Q6GUG4 Rat
- Unigene: 546396 Human
see all -
製品の状態
There are 2 isoforms produced by alternative splicing. -
別名
- P2RY13 antibody
- FKSG77 antibody
- G protein coupled receptor 86 antibody
see all
画像
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Western blot - Anti-P2Y13 antibody [EPR3698] (ab108444)All lanes : Anti-P2Y13 antibody [EPR3698] (ab108444) at 1/1000 dilution
Lane 1 : Human spleen tissue lysate
Lane 2 : HeLa cell lysate
Lane 3 : HepG2 cell lysate
Lane 4 : Jurkat cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 41 kDa -
![Anti-P2Y13 antibody [EPR3698] (ab108444)](https://www.abcam.co.jp/ps/products/108/ab108444/Images/ab108444-2-benefits-of-recombinant-antibodies.png)
Anti-P2Y13 antibody [EPR3698] (ab108444)
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab108444 は 3 報の論文で使用されています。
- Kyrargyri V et al. P2Y13 receptors regulate microglial morphology, surveillance, and resting levels of interleukin 1ß release. Glia 68:328-344 (2020). PubMed: 31520551
- Zhou R et al. Activation of spinal dorsal horn P2Y13 receptors can promote the expression of IL-1ß and IL-6 in rats with diabetic neuropathic pain. J Pain Res 11:615-628 (2018). PubMed: 29628771
- Niu J et al. Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12and P2Y13receptors in neuropathic pain rats. J Neuroinflammation 14:185 (2017). PubMed: 28899427