Anti-P2X3 抗体 (ab10269)
Key features and details
- Rabbit polyclonal to P2X3
- Suitable for: ICC, WB, IHC-Fr, ICC/IF, IHC-FoFr
- Reacts with: Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-P2X3 antibody
P2X3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to P2X3 -
由来種
Rabbit -
アプリケーション
適用あり: ICC, WB, IHC-Fr, ICC/IF, IHC-FoFrmore details -
種交差性
交差種: Rat, Human
交差が予測される動物種: Mouse, Non human primates
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免疫原
Synthetic peptide corresponding to Rat P2X3 aa 350 to the C-terminus (C terminal).
Database link: P49654 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.05% Sodium azide
Constituent: Whole serum -
Concentration information loading... -
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab10269の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC |
Use at an assay dependent concentration.
|
|
| WB | (1) |
Use at an assay dependent concentration.
|
| IHC-Fr | (2) |
Use at an assay dependent concentration.
|
| ICC/IF |
Use at an assay dependent concentration.
|
|
| IHC-FoFr |
1/100 - 1/300.
|
| 特記事項 |
|---|
|
ICC
Use at an assay dependent concentration. |
|
WB
Use at an assay dependent concentration. |
|
IHC-Fr
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. |
|
IHC-FoFr
1/100 - 1/300. |
ターゲット情報
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機能
Receptor for ATP that acts as a ligand-gated ion channel. -
配列類似性
Belongs to the P2X receptor family. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 5024 Human
- Entrez Gene: 228139 Mouse
- Entrez Gene: 81739 Rat
- Omim: 600843 Human
- SwissProt: P56373 Human
- SwissProt: Q3UR32 Mouse
- SwissProt: P49654 Rat
- Unigene: 146738 Human
see all -
別名
- ATP receptor antibody
- MGC129956 antibody
- P2rx3 antibody
see all
画像
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Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-P2X3 antibody (ab10269)
Image A: ab10248, at a dilution of 1/1000, staining P2X3 (green) in rat dorsal root ganglia sections by Immunohistochemistry (PFA perfusion fixed frozen sections). Other structures visualized with anti-ASIC3 (red).
Image B: Structures in rat dorsal root ganglia sections visualized with anti-ASIC3 (red) and anti-TRPV1 (green). Double-labeled cells are yellow or orange.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (13)
ab10269 は 13 報の論文で使用されています。
- Sun Q et al. Parathyroid hormone attenuates osteoarthritis pain by remodeling subchondral bone in mice. Elife 10:N/A (2021). PubMed: 33646122
- Ding S et al. Activation of ATF3/AP-1 signaling pathway is required for P2X3-induced endometriosis pain. Hum Reprod 35:1130-1144 (2020). PubMed: 32303740
- Cui Y et al. Resveratrol alleviates diabetic mechanical allodynia in rats by downregulating P2X3R. Mol Med Rep 22:957-963 (2020). PubMed: 32468070
- Zhang F et al. P2X3 Receptor in Primary Afferent Neurons Mediates the Relief of Visceral Hypersensitivity by Electroacupuncture in an Irritable Bowel Syndrome Rat Model. Gastroenterol Res Pract 2020:8186106 (2020). PubMed: 33014041
- Mailhot B et al. Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases. J Exp Med 217:N/A (2020). PubMed: 32573694