Anti-Oxytocin-neurophysin 1 抗体 (ab2078)
Key features and details
- Rabbit polyclonal to Oxytocin-neurophysin 1
- Suitable for: IHC-P, ICC/IF, IHC-FoFr
- Reacts with: Mouse, Rat, Sheep, Rabbit, Guinea pig, Human, Pig
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Oxytocin-neurophysin 1 antibody
Oxytocin-neurophysin 1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Oxytocin-neurophysin 1 -
由来種
Rabbit -
特異性
Less than 1% reactivity to vasopressin. -
アプリケーション
適用あり: IHC-P, ICC/IF, IHC-FoFrmore details -
種交差性
交差種: Mouse, Rat, Sheep, Rabbit, Guinea pig, Human, Pig -
免疫原
Full length protein corresponding to Oxytocin-neurophysin 1. Oxytocin-thyroglobulin
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituent: Whole serum -
Concentration information loading...
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精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab2078の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P | (1) |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration.
|
|
IHC-FoFr |
Use at an assay dependent concentration. PubMed: 20043984
|
特記事項 |
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IHC-P
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
IHC-FoFr
Use at an assay dependent concentration. PubMed: 20043984 |
ターゲット情報
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関連性
Neurophysin 1 specifically binds oxytocin. Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Oxytocin contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 5020 Human
- Entrez Gene: 18429 Mouse
- Entrez Gene: 25504 Rat
- Omim: 167050 Human
- SwissProt: P01178 Human
- SwissProt: P35454 Mouse
- SwissProt: P01177 Pig
- SwissProt: P13389 Sheep
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別名
- MGC126890 antibody
- MGC126892 antibody
- Neurophysin 1 antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (15)
ab2078 は 15 報の論文で使用されています。
- Ogata K et al. Lavender Oil Reduces Depressive Mood in Healthy Individuals and Enhances the Activity of Single Oxytocin Neurons of the Hypothalamus Isolated from Mice: A Preliminary Study. Evid Based Complement Alternat Med 2020:5418586 (2020). PubMed: 32733584
- Song TJ et al. Altered Behaviors and Impaired Synaptic Function in a Novel Rat Model With a Complete Shank3 Deletion. Front Cell Neurosci 13:111 (2019). PubMed: 30971895
- Mohan S et al. Oxytocin is present in islets and plays a role in beta-cell function and survival. Peptides 100:260-268 (2018). IF . PubMed: 29274352
- Zhang B et al. Central insulin action induces activation of paraventricular oxytocin neurons to release oxytocin into circulation. Sci Rep 8:10415 (2018). PubMed: 29991705
- Dai D et al. Direct Involvement of Androgen Receptor in Oxytocin Gene Expression: Possible Relevance for Mood Disorders. Neuropsychopharmacology 42:2064-2071 (2017). PubMed: 28447621