Anti-Ornithine Decarboxylase/ODC 抗体 (ab97395)
Key features and details
- Rabbit polyclonal to Ornithine Decarboxylase/ODC
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Ornithine Decarboxylase/ODC antibody
Ornithine Decarboxylase/ODC 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Ornithine Decarboxylase/ODC -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Mouse, Rat, Human
交差が予測される動物種: Cow, Pig -
免疫原
Recombinant fragment corresponding to Human Ornithine Decarboxylase/ODC aa 180-433.
Database link: P11926 -
ポジティブ・コントロール
- WB: HepG2 cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab97395の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/100 - 1/1000.
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WB |
1/1000. Predicted molecular weight: 51 kDa.
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特記事項 |
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IHC-P
1/100 - 1/1000. |
WB
1/1000. Predicted molecular weight: 51 kDa. |
ターゲット情報
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パスウェイ
Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1. -
配列類似性
Belongs to the Orn/Lys/Arg decarboxylase class-II family. -
翻訳後修飾
S-Nitrosylation inhibits the enzyme. S-Nitrosylated in vitro on 4 cysteine residues. - Information by UniProt
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参照データベース
- Entrez Gene: 281365 Cow
- Entrez Gene: 4953 Human
- Entrez Gene: 18263 Mouse
- Entrez Gene: 414408 Pig
- Entrez Gene: 24609 Rat
- Omim: 165640 Human
- SwissProt: P27117 Cow
- SwissProt: P11926 Human
see all -
別名
- DCOR_HUMAN antibody
- Dodc1 antibody
- Odc 1 antibody
see all
画像
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All lanes : Anti-Ornithine Decarboxylase/ODC antibody (ab97395) at 1/1000 dilution
Lane 1 : HepG2 whole cell lysate
Lane 2 : T47D whole cell lysate
Lysates/proteins at 30 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG antibody (HRP)
Predicted band size: 51 kDaThe signal was developed with Trident ECL plus-Enhanced.
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Paraffin embedded rat adrenal gland tissue stained for ODC using ab97395 at 1/500 dilution in immunohistochemical analysis.
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Paraffin embedded mouse heart tissue stained for ODC using ab97395 at 1/1000 dilution in immunohistochemical analysis.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (14)
ab97395 は 14 報の論文で使用されています。
- Park MG et al. DMSO-tolerant ornithine decarboxylase (ODC) tandem assay optimised for high-throughput screening. J Enzyme Inhib Med Chem 38:309-318 (2023). PubMed: 36451618
- Urban-Wójciuk Z et al. The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme. Cancer Gene Ther 29:940-950 (2022). PubMed: 34522028
- Zhao L et al. mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A. Cell Biosci 12:183 (2022). PubMed: 36371321
- Zhang X et al. Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway. Int J Mol Med 47:N/A (2021). PubMed: 33537831
- Halloran KM et al. Pre-implantation exogenous progesterone and pregnancy in sheep. II. Effects on fetal-placental development and nutrient transporters in late pregnancy. J Anim Sci Biotechnol 12:46 (2021). PubMed: 33827696