Anti-NOX2/gp91phox 抗体 (ab106940)
Key features and details
- Goat polyclonal to NOX2/gp91phox
- Suitable for: IHC
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-NOX2/gp91phox antibody
NOX2/gp91phox 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to NOX2/gp91phox -
由来種
Goat -
アプリケーション
適用あり: IHCmore details -
種交差性
交差種: Human
交差が予測される動物種: Dog -
免疫原
Synthetic peptide corresponding to Human NOX2/gp91phox aa 151-163 (internal sequence).
Sequence:C-SYLNFARKRIKNP
Database link: P04839 -
ポジティブ・コントロール
- IHC-P: Human placenta tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106940の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC |
Use a concentration of 2 - 4 µg/ml.
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特記事項 |
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IHC
Use a concentration of 2 - 4 µg/ml. |
ターゲット情報
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機能
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. -
関連疾患
Defects in CYBB are a cause of chronic granulomatous disease X-linked (XCGD) [MIM:306400]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections. -
配列類似性
Contains 1 FAD-binding FR-type domain.
Contains 1 ferric oxidoreductase domain. -
翻訳後修飾
Glycosylated. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 1536 Human
- Omim: 300481 Human
- SwissProt: P04839 Human
- Unigene: 292356 Human
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別名
- AMCBX2 antibody
- CGD antibody
- CGD91-phox antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (0)
ab106940 は論文での使用が確認できていません。