Anti-Nonspecific Cytotoxic Cells 抗体 [5C.6] (ab2778)
Key features and details
- Mouse monoclonal [5C.6] to Nonspecific Cytotoxic Cells
- Suitable for: Inhibition Assay, ELISA, IP, WB, Flow Cyt
- Reacts with: Rat, Horse, Cow, Dog, Pig, Tilapia, Catfish
- Isotype: IgM
製品の概要
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製品名
Anti-Nonspecific Cytotoxic Cells antibody [5C.6] -
製品の詳細
Mouse monoclonal [5C.6] to Nonspecific Cytotoxic Cells -
由来種
Mouse -
アプリケーション
適用あり: Inhibition Assay, ELISA, IP, WB, Flow Cytmore details -
種交差性
交差種: Rat, Horse, Cow, Dog, Pig, Tilapia, Catfish -
免疫原
Tissue, cells or virus corresponding to Nonspecific Cytotoxic Cells. Purified NCC cells from catfish.
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ポジティブ・コントロール
- This antibody as been successfully used in cytotoxic inhibition studies with NCC/NK/LAK cells, panning, and ELISA procedures. In cytotoxicity assays, this antibody is used under saturating conditions to inhibit target cell conjugation.
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特記事項
U.S. Patent Numbers: 5,028,424 and 5,229,494.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.05% Sodium azide
Constituent: 0.1% BSA -
Concentration information loading...
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精製度
Purified IgM -
一次抗体 備考
Non-specific cytotoxic cells (NCCs) in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. One such property is that NCC/natural killer (NK)/lymphokine activated killer (LAK) cells express spontaneous, non-major histocompatibility complex restricted cytotoxic activity. NCC and LAK lyse a variety of transformed murine and human B-cell, T-cell and myeloid targets. A 32 kDa membrane protein [non-specific cytotoxic cell receptor protein (NCCRP-1)] expressed by NCC and certain mammalian NK/LAK cells mediates this cytotoxicity. NCCRP-1 is evolutionarily conserved and is found in species ranging from marine and freshwater teleosts to higher mammals. -
ポリ/モノ
モノクローナル -
クローン名
5C.6 -
アイソタイプ
IgM -
研究分野
関連製品
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Compatible Secondaries
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab2778の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Inhibition Assay |
Use at an assay dependent concentration.
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ELISA |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
By Western blot, this antibody detects a 32 kDa protein representing nonspecific cytotoxic cell receptor protein. |
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Flow Cyt |
Use at an assay dependent concentration.
ab91545 - Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody. |
特記事項 |
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Inhibition Assay
Use at an assay dependent concentration. |
ELISA
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. By Western blot, this antibody detects a 32 kDa protein representing nonspecific cytotoxic cell receptor protein. |
Flow Cyt
Use at an assay dependent concentration. ab91545 - Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody. |
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (1)
ab2778 は 1 報の論文で使用されています。
- Jaso-Friedmann L et al. NCCRP-1: a novel receptor protein sequenced from teleost nonspecific cytotoxic cells. Mol Immunol 34:955-65 (1997). PubMed: 9464530