Anti-NMDAR2B (phospho Y1472) 抗体 (ab3856)

Submit a review Q&A (2)References (4)

Key features and details

  • Rabbit polyclonal to NMDAR2B (phospho Y1472)
  • Suitable for: WB
  • Reacts with: Rat
  • Isotype: IgG

製品の概要

  • 製品名

    Anti-NMDAR2B (phospho Y1472) antibody
    NMDAR2B 一次抗体 製品一覧

  • 製品の詳細

    Rabbit polyclonal to NMDAR2B (phospho Y1472)

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: WBmore details

  • 種交差性

    交差種: Rat

  • 免疫原

    Synthetic peptide (Rat).

  • ポジティブ･コントロール

    • Rat brain tissue lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab3856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Detects a band of approximately 180 kDa.

ターゲット情報

  • 機能

    NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

  • 組織特異性

    Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia.

  • 配列類似性

    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B subfamily.

  • 細胞内局在

    Cell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt

  • 参照データベース

    • 別名

      • AW490526 antibody
      • EIEE27 antibody
      • Glutamate [NMDA] receptor subunit epsilon 2 antibody
      • Glutamate [NMDA] receptor subunit epsilon-2 antibody
      • Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody
      • Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody
      • Glutamate receptor ionotropic NMDA2B antibody
      • Glutamate receptor subunit epsilon 2 antibody
      • Glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody
      • GRIN 2B antibody
      • GRIN2B antibody
      • hNR 3 antibody
      • hNR3 antibody
      • MGC142178 antibody
      • MGC142180 antibody
      • MRD6 antibody
      • N methyl D asparate receptor channel subunit epsilon 2 antibody
      • N methyl D aspartate receptor subtype 2B antibody
      • N methyl D aspartate receptor subunit 2B antibody
      • N methyl D aspartate receptor subunit 3 antibody
      • N-methyl D-aspartate receptor subtype 2B antibody
      • N-methyl-D-aspartate receptor subunit 3 antibody
      • NMDA NR2B antibody
      • NMDA R2B antibody
      • NMDAR2B antibody
      • NMDE2 antibody
      • NMDE2_HUMAN antibody
      • NME2 antibody
      • NR2B antibody
      • NR3 antibody
      see all

    参考文献 (4)

    ab3856 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab3856 は 4 報の論文で使用されています。

    • Li N  et al. LPM580098, a Novel Triple Reuptake Inhibitor of Serotonin, Noradrenaline, and Dopamine, Attenuates Neuropathic Pain. Front Pharmacol 10:53 (2019). PubMed: 30837867
    • Yang Q  et al. Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampus. EBioMedicine 47:470-483 (2019). PubMed: 31474551
    • Zhou R  et al. Activation of spinal dorsal horn P2Y13 receptors can promote the expression of IL-1ß and IL-6 in rats with diabetic neuropathic pain. J Pain Res 11:615-628 (2018). PubMed: 29628771
    • Fang YY  et al. Evidence of altered depression and dementia-related proteins in the brains of young rats after ovariectomy. J Neurochem 146:703-721 (2018). PubMed: 29939407

    レビューと Q&A

    Show All レビュー Q&A
    レビューを送る 質問を送る

    1-2 of 2 Abreviews or Q&A

    Question

    Inquiry: Hi abcam! I have a question regarding anti-p-NMDAR2B (pY1472) (ab3856). Do you have an example of a western blot run that I can see? from rat tissue preferable. I can see from the datasheet from antibody ab65783 that there is an extra/unidentified band at 35 kDa - is this the same for ab3856?

    Read More
    Answer

    We unfortunately do not have image for ab3856, however it has been tested with rat samples and is fully covered under Abpromise guarantee, https://www.abcam.com/content/abpromise-guarantee.



    In case you are interested in buying and trying this product then I would encourage you to participate in our 100% Abtrial Image discount programme - a free product can be claimed in your next order in-exchange for review of this product with image specific to rat samples. Please contact me with the order number for Abtrial code once the purchase is completed.


    More details about the offer can be found at the following link;


    https://www.abcam.com/index.html?pageconfig=resource&rid=11998&viapagetrap=collaborationdiscount



    This Abtrial offer was created to give scientists the opportunity to try products in an untested species or application, without the financial risk of failure.


    Please note if this product doesn’t work you can still claim a refund and free antibody under Abtrial code promotion.


    In relation to ab65783 we haven’t tested the identity of band at 35kDA so I am sorry we do not have any further information. This antibody is also comes with 100 money back guarantee so feel free to purchase and use this.

    Read More

    Question

    Dear Sir/Madam,  DCM Compliance manages Safety Data Sheets for a number of clients mainly in the healthcare industry. If possible could you send me on an SDS for the following products: ab7855 ·        ab3856 ·        ab60087 ·        ab64542 Huge thanks in advance  Kindest Regards      

    Read More
    Answer

    Thank you for contacting us. The MSDS can be downloaded online form our website. The link is given on every antibody datasheet in storage buffer section. Please also find attached with this email. Ab3856 does not contain any preservative so there is no MSDS for this product. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com