Anti-NMDAR2B 抗体 (ab216621)
Key features and details
- Rabbit polyclonal to NMDAR2B
- Suitable for: IHC-P
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-NMDAR2B antibody
NMDAR2B 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to NMDAR2B -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Rat
交差が予測される動物種: Mouse, Human -
免疫原
Synthetic peptide within Human NMDAR2B aa 465-515 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: Q13224 -
ポジティブ・コントロール
- Rat brain tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA, 48.98% TBS, 1X -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab216621の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P |
1/100 - 1/500.
(or 1/50 - 1/200 if using a fluorescent secondary antibody). |
特記事項 |
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IHC-P
1/100 - 1/500. (or 1/50 - 1/200 if using a fluorescent secondary antibody). |
ターゲット情報
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機能
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. -
組織特異性
Primarily found in the fronto-parieto-temporal cortex and hippocampus pyramidal cells, lower expression in the basal ganglia. -
配列類似性
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B subfamily. -
細胞内局在
Cell membrane. Cell junction > synapse > postsynaptic cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 2904 Human
- Entrez Gene: 14812 Mouse
- Entrez Gene: 24410 Rat
- Omim: 138252 Human
- SwissProt: Q13224 Human
- SwissProt: Q01097 Mouse
- SwissProt: Q00960 Rat
- Unigene: 654430 Human
see all -
別名
- AW490526 antibody
- EIEE27 antibody
- Glutamate [NMDA] receptor subunit epsilon 2 antibody
see all
画像
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat brain tissue labeling NMDAR2B with ab216621 at 1/300 dilution, followed by conjugation to the secondary antibody and DAB staining.
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat brain tissue labeling NMDAR2B with ab216621 at 1/200 dilution, followed by Goat anti-Rabbit IgG, FITC conjugate at 1/200 dilution for 40 minutes at 37°C and DAPI staining.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab216621 は 1 報の論文で使用されています。
- Zhao L et al. Effects of intrathecal bupivacaine on the NR2B/CaMKIIa/CREB signaling pathway in the rat lumbar spinal cord. Mol Med Rep 17:4508-4514 (2018). PubMed: 29344649