Nicastrin peptide (ab4977)
製品の詳細
-
製品名
Nicastrin peptide -
Animal free
No -
由来
Synthetic
関連製品
-
Related Products
特性
Our Abpromise guarantee covers the use of ab4977 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
アプリケーション
Blocking
-
製品の状態
Liquid -
備考
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human nicastrin, catalog ab3444. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.
-
Concentration information loading...
前処理および保存
-
保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
関連情報
-
別名
- Anterior pharynx defective 2
- APH 2
- APH2
see all -
機能
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex. -
組織特異性
Widely expressed. -
配列類似性
Belongs to the nicastrin family. -
細胞内局在
Membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
参考文献 (0)
ab4977 は論文での使用が確認できていません。
