Anti-Neuropeptide Y 抗体 (ab6173)
Key features and details
- Sheep polyclonal to Neuropeptide Y
- Reacts with: Rabbit, Guinea pig, Human
- Isotype: IgG
製品の概要
-
製品名
Anti-Neuropeptide Y antibody
Neuropeptide Y 一次抗体 製品一覧 -
製品の詳細
Sheep polyclonal to Neuropeptide Y -
由来種
Sheep -
特異性
The specificity of the NPY antiserum was determined by radioimmunoassay. Synthetic peptides, somatostatin-14, leu-enkephalin, met-enkephalin, oxytocin, Arg8-vasopressin, vasoactive intestinal peptide, angiotensin II demonstrated less than 0.005% cross- reactivity and substance P less than 0.02%. Peptide YY and bovine pancreatic polypeptide demonstrated approx. 36% and 0.05% cross- reactivity respectively. Human peptide YY share 65% homology amino acid sequence for human NPY. Synthetic NPY completely abolished radio labelled NPY binding to NPY antibody in RIA and antibody binding to tissue antigen. -
種交差性
交差種: Rabbit, Guinea pig, Human -
免疫原
Synthetic peptide:
TPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY
, corresponding to amino acids 30-64 of Human Neuropeptide Y. The peptide was coupled to Bovine Thyroglobulin. -
特記事項
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Concentration information loading... -
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Isotype control
-
Recombinant Protein
ターゲット情報
-
機能
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. -
組織特異性
One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. -
配列類似性
Belongs to the NPY family. -
細胞内局在
Secreted. - Information by UniProt
-
参照データベース
- Entrez Gene: 100724008 Guinea pig
- Entrez Gene: 4852 Human
- Omim: 162640 Human
- SwissProt: P01303 Human
- SwissProt: P68006 Rabbit
- Unigene: 1832 Human
-
別名
- C-flanking peptide of NPY antibody
- CPON antibody
- Neuropeptide tyrosine antibody
see all
データシートおよび資料
参考文献 (13)
ab6173 は 13 報の論文で使用されています。
- Shu Q et al. Acupuncture Targeting SIRT1 in the Hypothalamic Arcuate Nucleus Can Improve Obesity in High-Fat-Diet-Induced Rats with Insulin Resistance via an Anorectic Effect. Obes Facts 13:40-57 (2020). PubMed: 31935731
- Damasceno S et al. Top Common Differentially Expressed Genes in the Epileptogenic Nucleus of Two Strains of Rodents Susceptible to Audiogenic Seizures: WAR and GASH/Sal. Front Neurol 11:33 (2020). PubMed: 32117006
- Robinson SL et al. Medial prefrontal cortex neuropeptide Y modulates binge-like ethanol consumption in C57BL/6J mice. Neuropsychopharmacology 44:1132-1140 (2019). PubMed: 30647448
- Huang X et al. Effects of electroacupuncture on luteal regression and steroidogenesis in ovarian hyperstimulation syndrome model rat. Life Sci 197:1-9 (2018). WB . PubMed: 29482802
- Wang R et al. Neuropeptide Y-Positive Neurons in the Dorsomedial Hypothalamus Are Involved in the Anorexic Effect of Angptl8. Front Mol Neurosci 11:451 (2018). PubMed: 30618603
