Anti-Neuropeptide Y 抗体 (ab6173)
Key features and details
- Sheep polyclonal to Neuropeptide Y
- Reacts with: Rabbit, Guinea pig, Human
- Isotype: IgG
製品の概要
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製品名
Anti-Neuropeptide Y antibody
Neuropeptide Y 一次抗体 製品一覧 -
製品の詳細
Sheep polyclonal to Neuropeptide Y -
由来種
Sheep -
特異性
The specificity of the NPY antiserum was determined by radioimmunoassay. Synthetic peptides, somatostatin-14, leu-enkephalin, met-enkephalin, oxytocin, Arg8-vasopressin, vasoactive intestinal peptide, angiotensin II demonstrated less than 0.005% cross- reactivity and substance P less than 0.02%. Peptide YY and bovine pancreatic polypeptide demonstrated approx. 36% and 0.05% cross- reactivity respectively. Human peptide YY share 65% homology amino acid sequence for human NPY. Synthetic NPY completely abolished radio labelled NPY binding to NPY antibody in RIA and antibody binding to tissue antigen. -
種交差性
交差種: Rabbit, Guinea pig, Human -
免疫原
Synthetic peptide:
TPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY
, corresponding to amino acids 30-64 of Human Neuropeptide Y. The peptide was coupled to Bovine Thyroglobulin. -
特記事項
This antibody is excellent for immunohistochemistry. Good staining was achieved in rabbit brain and guinea pig gastrointestinal tract.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Concentration information loading... -
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
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Recombinant Protein
ターゲット情報
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機能
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. -
組織特異性
One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. -
配列類似性
Belongs to the NPY family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 100724008 Guinea pig
- Entrez Gene: 4852 Human
- Omim: 162640 Human
- SwissProt: P01303 Human
- SwissProt: P68006 Rabbit
- Unigene: 1832 Human
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別名
- C-flanking peptide of NPY antibody
- CPON antibody
- Neuropeptide tyrosine antibody
see all
データシートおよび資料
参考文献 (10)
ab6173 は 10 報の論文で使用されています。
- Huang X et al. Effects of electroacupuncture on luteal regression and steroidogenesis in ovarian hyperstimulation syndrome model rat. Life Sci 197:1-9 (2018). WB . PubMed: 29482802
- Wang R et al. Neuropeptide Y-Positive Neurons in the Dorsomedial Hypothalamus Are Involved in the Anorexic Effect of Angptl8. Front Mol Neurosci 11:451 (2018). PubMed: 30618603
- Thangaratnarajah C et al. Novel role of NPY in neuroimmune interaction and lung growth after intrauterine growth restriction. Am J Physiol Lung Cell Mol Physiol 313:L491-L506 (2017). PubMed: 28572154
- Filipovic N et al. Expression of PTHrP and PTH/PTHrP receptor 1 in the superior cervical ganglia of rats. Neuropeptides 48:353-9 (2014). PubMed: 25278090
- Furlan A et al. The transcription factor Hmx1 and growth factor receptor activities control sympathetic neurons diversification. EMBO J 32:1613-25 (2013). PubMed: 23591430
- Rubin AN & Kessaris N PROX1: A Lineage Tracer for Cortical Interneurons Originating in the Lateral/Caudal Ganglionic Eminence and Preoptic Area. PLoS One 8:e77339 (2013). IHC-Fr ; Mouse . PubMed: 24155945
- Lee S et al. The largest group of superficial neocortical GABAergic interneurons expresses ionotropic serotonin receptors. J Neurosci 30:16796-808 (2010). IHC ; Mouse . PubMed: 21159951
- Oboti L et al. Integration and sensory experience-dependent survival of newly-generated neurons in the accessory olfactory bulb of female mice. Eur J Neurosci 29:679-92 (2009). IHC-FoFr ; Mouse . PubMed: 19200078
- Zhang J et al. Adrenergic activation of electrogenic K+ secretion in guinea pig distal colonic epithelium: desensitization via the Y2-neuropeptide receptor. Am J Physiol Gastrointest Liver Physiol 297:G278-91 (2009). IF, IHC ; Guinea pig . PubMed: 19497958
- Czaja K et al. Leptin receptors, NPY, and tyrosine hydroxylase in autonomic neurons supplying fat depots in a pig. Biochem Biophys Res Commun 293:1138-44 (2002). PubMed: 12051778
