Anti-Neuropeptide Y 抗体 (ab6173)
Key features and details
- Sheep polyclonal to Neuropeptide Y
- Reacts with: Rabbit, Guinea pig, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Neuropeptide Y antibody
Neuropeptide Y 一次抗体 製品一覧 -
製品の詳細
Sheep polyclonal to Neuropeptide Y -
由来種
Sheep -
特異性
The specificity of the NPY antiserum was determined by radioimmunoassay. Synthetic peptides, somatostatin-14, leu-enkephalin, met-enkephalin, oxytocin, Arg8-vasopressin, vasoactive intestinal peptide, angiotensin II demonstrated less than 0.005% cross- reactivity and substance P less than 0.02%. Peptide YY and bovine pancreatic polypeptide demonstrated approx. 36% and 0.05% cross- reactivity respectively. Human peptide YY share 65% homology amino acid sequence for human NPY. Synthetic NPY completely abolished radio labelled NPY binding to NPY antibody in RIA and antibody binding to tissue antigen. -
種交差性
交差種: Rabbit, Guinea pig, Human -
免疫原
Synthetic peptide:
TPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY
, corresponding to amino acids 30-64 of Human Neuropeptide Y. The peptide was coupled to Bovine Thyroglobulin. -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Concentration information loading... -
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
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Recombinant Protein
ターゲット情報
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機能
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. -
組織特異性
One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. -
配列類似性
Belongs to the NPY family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 100724008 Guinea pig
- Entrez Gene: 4852 Human
- Omim: 162640 Human
- SwissProt: P01303 Human
- SwissProt: P68006 Rabbit
- Unigene: 1832 Human
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別名
- C-flanking peptide of NPY antibody
- CPON antibody
- Neuropeptide tyrosine antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (13)
ab6173 は 13 報の論文で使用されています。
- Shu Q et al. Acupuncture Targeting SIRT1 in the Hypothalamic Arcuate Nucleus Can Improve Obesity in High-Fat-Diet-Induced Rats with Insulin Resistance via an Anorectic Effect. Obes Facts 13:40-57 (2020). PubMed: 31935731
- Damasceno S et al. Top Common Differentially Expressed Genes in the Epileptogenic Nucleus of Two Strains of Rodents Susceptible to Audiogenic Seizures: WAR and GASH/Sal. Front Neurol 11:33 (2020). PubMed: 32117006
- Robinson SL et al. Medial prefrontal cortex neuropeptide Y modulates binge-like ethanol consumption in C57BL/6J mice. Neuropsychopharmacology 44:1132-1140 (2019). PubMed: 30647448
- Huang X et al. Effects of electroacupuncture on luteal regression and steroidogenesis in ovarian hyperstimulation syndrome model rat. Life Sci 197:1-9 (2018). WB . PubMed: 29482802
- Wang R et al. Neuropeptide Y-Positive Neurons in the Dorsomedial Hypothalamus Are Involved in the Anorexic Effect of Angptl8. Front Mol Neurosci 11:451 (2018). PubMed: 30618603
レビューと Q&A
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