Anti-NEDL2 抗体 (ab92711)
Key features and details
- Rabbit polyclonal to NEDL2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-NEDL2 antibody
NEDL2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to NEDL2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide derived from an internal region of Human NEDL2.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading...
-
精製度
Immunogen affinity purified -
特記事項(精製)
The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab92711の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/500 - 1/1000. Predicted molecular weight: 176 kDa.
|
特記事項 |
---|
WB
1/500 - 1/1000. Predicted molecular weight: 176 kDa. |
ターゲット情報
-
機能
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. -
組織特異性
Predominantly expressed in adult brain, lung and heart. -
パスウェイ
Protein modification; protein ubiquitination. -
配列類似性
Contains 1 C2 domain.
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Contains 2 WW domains. -
細胞内局在
Cytoplasm. - Information by UniProt
-
参照データベース
- Entrez Gene: 57520 Human
- SwissProt: Q9P2P5 Human
- Unigene: 654742 Human
-
別名
- C2 and WW domain-containing protein 2 antibody
- E3 ubiquitin protein ligase HECW2 antibody
- E3 ubiquitin-protein ligase HECW2 antibody
see all
画像
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (2)
ab92711 は 2 報の論文で使用されています。
- Mao J et al. NEDD4-like ubiquitin ligase 2 protein (NEDL2) in porcine spermatozoa, oocytes, and preimplantation embryos and its role in oocyte fertilization†. Biol Reprod 104:117-129 (2021). PubMed: 33030211
- Qiu X et al. NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner. Oncotarget 7:31440-53 (2016). PubMed: 27119228