精製度> 95 % SDS-PAGE.
Our Abpromise guarantee covers the use of ab5896 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat Excanger (Na/Ca-k), catalog ab3507. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.
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Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
再構成Reconstitute with 0.1 ml of distilled water.
- Na(+)/K(+)/Ca(2+) exchange protein 2
- Na(+)/K(+)/Ca(2+)-exchange protein 2
- NCKX 2
機能Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
配列類似性Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.