Anti-Myeloperoxidase 抗体 [2D4] (ab90810)
Key features and details
- Mouse monoclonal [2D4] to Myeloperoxidase
- Suitable for: ICC/IF
- Reacts with: Rat
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
Anti-Myeloperoxidase antibody [2D4]
Myeloperoxidase 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [2D4] to Myeloperoxidase -
由来種
Mouse -
アプリケーション
適用あり: ICC/IFmore details
適用なし: IHC-P or WB -
種交差性
交差種: Rat -
免疫原
Full length native protein (purified). This information is proprietary to Abcam and/or its suppliers.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
ab90810 is provided as a 0.2 µm filtered solution. -
ポリ/モノ
モノクローナル -
クローン名
2D4 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Assay kits
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab90810の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC/IF |
1/50.
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特記事項 |
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ICC/IF
1/50. |
ターゲット情報
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機能
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. -
関連疾患
Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis. -
配列類似性
Belongs to the peroxidase family. XPO subfamily. -
細胞内局在
Lysosome. - Information by UniProt
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参照データベース
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別名
- 84 kDa myeloperoxidase antibody
- 89 kDa myeloperoxidase antibody
- EC 1.11.1.7 antibody
see all
画像
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (19)
ab90810 は 19 報の論文で使用されています。
- Guy R et al. A Novel Rodent Model of Hypertensive Cerebral Small Vessel Disease with White Matter Hyperintensities and Peripheral Oxidative Stress. Int J Mol Sci 23:N/A (2022). PubMed: 35682594
- Wang Y et al. Neutrophil Extracellular Traps (NETs) Promote Non-Small Cell Lung Cancer Metastasis by Suppressing lncRNA MIR503HG to Activate the NF-κB/NLRP3 Inflammasome Pathway. Front Immunol 13:867516 (2022). PubMed: 35707534
- Li JC et al. Neutrophil extracellular traps participate in the development of cancer-associated thrombosis in patients with gastric cancer. World J Gastroenterol 28:3132-3149 (2022). PubMed: 36051331
- Arnold S et al. Single and Multiplex Immunohistochemistry to Detect Platelets and Neutrophils in Rat and Porcine Tissues. Methods Protoc 5:N/A (2022). PubMed: 36136817
- Weng J et al. Augmenter of liver regeneration ameliorates ischemia-reperfusion injury in steatotic liver via inhibition of the TLR4/NF-?B pathway. Exp Ther Med 22:863 (2021). PubMed: 34178136