Anti-Mycobacterium tuberculosis 抗体 (ab905)
製品の概要
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製品名Anti-Mycobacterium tuberculosis antibody
Mycobacterium tuberculosis 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to Mycobacterium tuberculosis
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由来種Rabbit
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特異性This antibody is reactive with other Mycobacteria species including: M. avium, M. phlei, and M. parafortuitum. This antibody has been reported not to be reactive with E. coli K12, Salmonella typhimurium, Pseudomonas aeruginosa, Streptococcus (group B), Candida albicans and Neisseria meningitides.
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アプリケーション適用あり: ICC/IF, IHC-P, IHC-Frmore details
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種交差性
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免疫原
Purified Protein Derivative
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ポジティブ・コントロール
- Infected lung
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーPreservative: 0.1% Sodium Azide
Constituents: PBS, Carrier protein, Da Vinci Green Diluent, pH 7.3 -
Concentration information loading...
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精製度IgG fraction
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Antibody Diluent
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Compatible Secondaries
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Isotype control
アプリケーション
Our Abpromise guarantee covers the use of ab905 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
アプリケーション | Abreviews | 特記事項 |
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ICC/IF | Use at an assay dependent concentration. PubMed: 24475192 | |
IHC-P | 1/100 - 1/200. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. ABC method. | |
IHC-Fr | 1/100 - 1/200. ABC method. |
ターゲット情報
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関連性Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.
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別名
- M. tuberculosis antibody
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参考文献
This product has been referenced in:
- Parasa VR et al. Evaluation of the immunogenic capability of the BCG strains BCG?BCG1419c and BCG?BCG1416c in a three-dimensional human lung tissue model. Vaccine 36:1811-1815 (2018). Read more (PubMed: 29475763) »
- Kayanuma H et al. Disseminated nontuberculous mycobacterial disease in a cat caused by Mycobacterium sp. strain MFM001. Vet Microbiol 220:90-96 (2018). Read more (PubMed: 29885807) »