Anti-MTA3 抗体 [EPR12777(B)] (ab176346)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR12777(B)] to MTA3
- Suitable for: Flow Cyt (Intra), WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-MTA3 antibody [EPR12777(B)]
MTA3 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR12777(B)] to MTA3 -
由来種
Rabbit -
アプリケーション
適用あり: Flow Cyt (Intra), WBmore details
適用なし: ICC/IF,IHC-P or IP -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide within Human MTA3 aa 400-500 (Cysteine residue). The exact sequence is proprietary.
Database link: Q9BTC8 -
ポジティブ・コントロール
- Permeabilized Ramos cells; T47-D, HeLa, MCF-7 and Ramos cell lysates
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
EPR12777(B) -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab176346の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt (Intra) |
1/10 - 1/100.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
|
WB |
1/1000 - 1/10000. Predicted molecular weight: 68 kDa.
|
特記事項 |
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Flow Cyt (Intra)
1/10 - 1/100. ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
WB
1/1000 - 1/10000. Predicted molecular weight: 68 kDa. |
ターゲット情報
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機能
Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. -
組織特異性
No expression in nonepithelial cells. -
配列類似性
Contains 1 BAH domain.
Contains 1 ELM2 domain.
Contains 1 GATA-type zinc finger.
Contains 1 SANT domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 57504 Human
- Entrez Gene: 116871 Mouse
- Entrez Gene: 298763 Rat
- Omim: 609050 Human
- SwissProt: Q9BTC8 Human
- SwissProt: Q924K8 Mouse
- Unigene: 435413 Human
- Unigene: 277668 Mouse
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別名
- 1110002J22Rik antibody
- fj99h01 antibody
- KIAA1266 antibody
see all
画像
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All lanes : Anti-MTA3 antibody [EPR12777(B)] (ab176346) at 1/1000 dilution
Lane 1 : T47D cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : MCF7 cell lysate
Lane 4 : Ramos cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 68 kDa -
Intracellular flow cytometric analysis of permeabilized Ramos cells labeling MTA3with ab176346 at 1/10 dilution (red)or a rabbit IgG (negative) (green).
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab176346 は 4 報の論文で使用されています。
- Xiaomeng F et al. Treatment with ß-elemene combined with paclitaxel inhibits growth, migration, and invasion and induces apoptosis of ovarian cancer cells by activation of STAT-NF-?B pathway. Braz J Med Biol Res 53:e8885 (2020). PubMed: 32401925
- Li Q et al. High glucose promotes hepatic fibrosis via miR-32/MTA3-mediated epithelial-to-mesenchymal transition. Mol Med Rep 19:3190-3200 (2019). PubMed: 30816482
- Wang Z et al. ß-elemene enhances anticancer bone neoplasms efficacy of paclitaxel through regulation of GPR124 in bone neoplasms cells. Oncol Lett 16:2143-2150 (2018). PubMed: 30008912
- Wei FZ et al. Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway. Autophagy 11:2309-22 (2015). PubMed: 26735435