製品の概要

  • 製品名

    MRS 2179, P2Y1 antagonist
  • 製品の詳細

    Potent, selective P2Y1 antagonist
  • 生理活性の詳細

    Potent, selective, competitive P2Y1 antagonist (Ki = 100 nM). Inhibits ATP induced glutamate release in vitro and inhibits ADP ability to evoke platelet shape change and aggregation.
  • 精製度

    > 98%
  • CAS 番号

    101204-49-3
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Zeng JW  et al. Inhibition of ATP-induced glutamate release by MRS2179 in cultured dorsal spinal cord astrocytes. Pharmacology 82:257-63 (2008). Read more (PubMed: 18841035) »
  • Kaiser RA & Buxton IL Nucleotide-mediated relaxation in guinea-pig aorta: selective inhibition by MRS2179. Br J Pharmacol 135:537-45 (2002). Read more (PubMed: 11815389) »
  • King BF 2-Chloro-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate is a selective high affinity P2Y1 receptor antagonist: commentary on Boyer et al. Br J Pharmacol 135:1839-40 (2002). Read more (PubMed: 11959784) »
See all 3 Publications for this product

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