Anti-MPP1 抗体 (ab96255)
Key features and details
- Rabbit polyclonal to MPP1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-MPP1 antibody
MPP1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to MPP1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rabbit, Cow -
免疫原
Recombinant fragment containing a sequence corresponding to a region within amino acids 214-398 of Human MPP1 (NP_002427).
-
ポジティブ・コントロール
- HeLa whole cell lysate, Cal27 xenograft; 293T, A431, H1299, HepG2, Molt-4 and Raji cell lysates
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab96255の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 52 kDa.
|
|
IHC-P |
1/100 - 1/500.
|
特記事項 |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 52 kDa. |
IHC-P
1/100 - 1/500. |
ターゲット情報
-
機能
Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity. -
組織特異性
Ubiquitous. -
配列類似性
Belongs to the MAGUK family.
Contains 1 guanylate kinase-like domain.
Contains 1 PDZ (DHR) domain.
Contains 1 SH3 domain. -
翻訳後修飾
Extensively palmitoylated. -
細胞内局在
Membrane. Cell projection > stereocilium. Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non-myelin-forming Schwann cells. - Information by UniProt
-
参照データベース
- Entrez Gene: 510998 Cow
- Entrez Gene: 4354 Human
- Entrez Gene: 17524 Mouse
- Entrez Gene: 100328768 Rabbit
- Omim: 305360 Human
- SwissProt: Q17QN6 Cow
- SwissProt: Q00013 Human
- SwissProt: P70290 Mouse
see all -
別名
- 55 kDa erythrocyte membrane protein antibody
- AAG 12 antibody
- AAG12 antibody
see all
画像
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab96255 は 1 報の論文で使用されています。
- Huang NJ et al. Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin. Nat Commun 8:423 (2017). PubMed: 28871080