Mouse Vitronectin ELISA kit (ab272778)
Key features and details
- Range: 0.1 ng/ml - 100 ng/ml
- Sample type: Cit plasma, EDTA Plasma, Hep Plasma, Other biological fluids
- Detection method: Colorimetric
- Assay type: Quantitative
製品の概要
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製品名
Mouse Vitronectin ELISA kit
Vitronectin/S-Protein キット 製品一覧 -
検出方法
Colorimetric -
再現性
Intra-Assay(同時再現性) サンプル N 平均値 SD CV% Sample 1 20 0.45ng/ml 7.69% Sample 2 20 3.02ng/ml 4.67% Sample 3 20 6.57ng/ml 5.7% -
サンプルの種類
Other biological fluids, Hep Plasma, EDTA Plasma, Cit plasma -
アッセイタイプ
Quantitative -
検出範囲
0.1 ng/ml - 100 ng/ml -
ステップ
Multiple steps standard assay -
試験プラットフォーム
Microplate
製品の特性
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保存方法
Store at +4°C. Please refer to protocols. -
内容 1 x 96 tests 10X Wash Buffer 1 x 50ml Anti-Mouse Vitronectin Primary Antibody Lyophilized Vial 1 vial Mouse Vitronectin ELISA Plate 1 unit Mouse Vitronection Standard Lyophilized Vial 1 vial Streptavidin-HRP Secondary Reagent 1 vial TMB Substrate 1 x 10ml -
研究分野
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機能
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity. -
組織特異性
Plasma. -
配列類似性
Contains 4 hemopexin repeats.
Contains 1 SMB (somatomedin-B) domain. -
ドメイン
The SMB domain mediates interaction with SERPINE1/PAI1. The heparin-binding domain mediates interaction with insulin. -
翻訳後修飾
Sulfated on 2 tyrosine residues.
N- and O-glycosylated.
Phosphorylation on Thr-69 and Thr-76 favors cell adhesion and spreading.
It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.
Phosphorylation sites are present in the extracellular medium. -
細胞内局在
Secreted, extracellular space. - Information by UniProt
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別名
- Complement S Protein
- Epibolin
- S Protein
see all -
参照データベース
- Entrez Gene: 22370 Mouse
- SwissProt: P29788 Mouse
関連製品
参考文献 (0)
ab272778 は論文での使用が確認できていません。