MMS2 一次抗体 製品一覧
製品の詳細Goat polyclonal to MMS2
アプリケーション適用あり: WBmore details
交差が予測される動物種: Mouse, Rat
- Human Brain lysate.
特記事項Principal Names – UBE2V2; ubiquitin-conjugating enzyme E2 variant 2; MMS2; UEV2; EDPF1; UEV-2; DDVIT1; EDAF-1; EDPF-1; DDVit-1; 1 alpha,25-dihydroxyvitamin D3-inducible; enterocyte differentiation promoting factor; methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of Official Gene Symbol - UBE2V2. GenBank Accession Number – NP_003341. LocusLink ID - 7336 (human); 70620 (mouse). Gene Ontology terms - cell proliferation; polyubiquitination; regulation of DNA repair; regulation of cell cycle; ubiquitin conjugating enzyme.
This product was previously labelled as Ube2v2, MMS2
保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium azide
Constituents: 0.05% Tris, 0.5% BSA
Concentration information loading...
精製度Immunogen affinity purified
特記事項（精製）Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Cell Biology
- Proteolysis / Ubiquitin
- Proteasome / Ubiquitin
- Ubiquitin E3 Enzymes
- RING Finger E3 Ligase
Our Abpromise guarantee covers the use of ab2513 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.2 - 1 µg/ml.
Approx 20kDa band seen in Human Brain lysate.
機能Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
組織特異性Detected in placenta, colon, liver and skin. Detected at very low levels in most tissues.
配列類似性Belongs to the ubiquitin-conjugating enzyme family.
- Information by UniProt
- 1 alpha 25 dihydroxyvitamin D3 inducible antibody
- DDVit 1 antibody
- DDVIT1 antibody
ab2513 has not yet been referenced specifically in any publications.