Anti-MMP3 抗体 [SL-1 ID3] (ab3204)

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Key features and details

  • Mouse monoclonal [SL-1 ID3] to MMP3
  • Reacts with: Human
  • Isotype: IgG1

製品の概要

  • 製品名

    Anti-MMP3 antibody [SL-1 ID3]
    MMP3 一次抗体 製品一覧

  • 製品の詳細

    Mouse monoclonal [SL-1 ID3] to MMP3

  • 由来種

    Mouse

  • 特異性

    ab3204 reacts with both pro and active forms of MMP 3.

  • 種交差性

    交差種: Human

  • 免疫原

    APMA (4 Aminophenylmercuric acetate) activated Human stromelysin 1 (SL 1).

  • ポジティブ･コントロール

    • Conditioned serum-free medium from TPA treated human Endometrial cells.

  • 特記事項

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

アプリケーション

  • 追加情報
    Is unsuitable for IHC-P.

    • ターゲット情報

    • 機能

      Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.

    • 配列類似性

      Belongs to the peptidase M10A family.
      Contains 4 hemopexin-like domains.

    • ドメイン

      The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.

    • 細胞内局在

      Secreted > extracellular space > extracellular matrix.
    • Information by UniProt

    • 参照データベース

      • 別名

        • CHDS6 antibody
        • Matrix metalloproteinase 3 antibody
        • Matrix metalloproteinase 3 preproprotein antibody
        • Matrix metalloproteinase-3 antibody
        • MGC126102 antibody
        • MGC126103 antibody
        • MGC126104 antibody
        • MMP 3 antibody
        • MMP-3 antibody
        • MMP3 antibody
        • MMP3_HUMAN antibody
        • Proteoglycanase antibody
        • SL-1 antibody
        • SL1 antibody
        • STMY antibody
        • STMY1 antibody
        • STR1 antibody
        • Stromelisin 1 antibody
        • Stromelysin 1 antibody
        • Stromelysin 1 progelatinase antibody
        • Stromelysin-1 antibody
        • Transin 1 antibody
        • Transin-1 antibody
        see all

      参考文献 (1)

      ab3204 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

      ab3204 は 1 報の論文で使用されています。

      • Wang L  et al. Berberine inhibits the ischemia-reperfusion injury induced inflammatory response and apoptosis of myocardial cells through the phosphoinositide 3-kinase/RAC-a serine/threonine-protein kinase and nuclear factor-?B signaling pathways. Exp Ther Med 15:1225-1232 (2018). PubMed: 29403554

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