Anti-MMP3 抗体 [SL-1 ID3] (ab3204)
Key features and details
- Mouse monoclonal [SL-1 ID3] to MMP3
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-MMP3 antibody [SL-1 ID3]
MMP3 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [SL-1 ID3] to MMP3 -
由来種
Mouse -
特異性
ab3204 reacts with both pro and active forms of MMP 3. -
種交差性
交差種: Human -
免疫原
APMA (4 Aminophenylmercuric acetate) activated Human stromelysin 1 (SL 1).
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ポジティブ･コントロール
- Conditioned serum-free medium from TPA treated human Endometrial cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
SL-1 ID3 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
追加情報
Is unsuitable for IHC-P.
ターゲット情報
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機能
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. -
配列類似性
Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains. -
ドメイン
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme. -
細胞内局在
Secreted > extracellular space > extracellular matrix. - Information by UniProt
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参照データベース
- Entrez Gene: 4314 Human
- Omim: 185250 Human
- SwissProt: P08254 Human
- Unigene: 375129 Human
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別名
- CHDS6 antibody
- Matrix metalloproteinase 3 antibody
- Matrix metalloproteinase 3 preproprotein antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab3204 は 1 報の論文で使用されています。
- Wang L et al. Berberine inhibits the ischemia-reperfusion injury induced inflammatory response and apoptosis of myocardial cells through the phosphoinositide 3-kinase/RAC-a serine/threonine-protein kinase and nuclear factor-?B signaling pathways. Exp Ther Med 15:1225-1232 (2018). PubMed: 29403554