Anti-MMP3 抗体 [SL-1 ID3] (ab3204)
Key features and details
- Mouse monoclonal [SL-1 ID3] to MMP3
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG1
製品の概要
-
製品名
Anti-MMP3 antibody [SL-1 ID3]
MMP3 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [SL-1 ID3] to MMP3 -
由来種
Mouse -
特異性
ab3204 reacts with both pro and active forms of MMP 3. -
アプリケーション
適用あり: WB, ICC/IFmore details
適用なし: IHC-P -
種交差性
交差種: Human -
免疫原
APMA (4 Aminophenylmercuric acetate) activated Human stromelysin 1 (SL 1).
-
ポジティブ･コントロール
- Conditioned serum-free medium from TPA treated human Endometrial cells.
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
SL-1 ID3 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
Our Abpromise guarantee covers the use of ab3204 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 2 - 4 µg/ml. Predicted molecular weight: 54 kDa. Incubate for 2 hours at room temperature. | |
| ICC/IF | Use at an assay dependent concentration. |
追加情報
Is unsuitable for IHC-P.
ターゲット情報
-
機能
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. -
配列類似性
Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains. -
ドメイン
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme. -
細胞内局在
Secreted > extracellular space > extracellular matrix. - Information by UniProt
-
参照データベース
- Entrez Gene: 4314 Human
- Omim: 185250 Human
- SwissProt: P08254 Human
- Unigene: 375129 Human
-
別名
- CHDS6 antibody
- Matrix metalloproteinase 3 antibody
- Matrix metalloproteinase 3 preproprotein antibody
see all
プロトコール
参考文献 (1)
ab3204 は 1 報の論文で使用されています。
- Wang L et al. Berberine inhibits the ischemia-reperfusion injury induced inflammatory response and apoptosis of myocardial cells through the phosphoinositide 3-kinase/RAC-a serine/threonine-protein kinase and nuclear factor-?B signaling pathways. Exp Ther Med 15:1225-1232 (2018). PubMed: 29403554
