製品の概要

  • 製品名

    Mitomycin C (MMC), Anticancer and antibiotic agent
  • 製品の詳細

    Anticancer and antibiotic agent
  • 別名

    • MMC
  • 生理活性の詳細

    Anticancer and antibiotic agent. Crosslinks DNA. Inhibits DNA synthesis and nuclear division. Also induces apoptosis.

  • 精製度

    > 99%
  • CAS 番号

    50-07-7
  • 構造式

    Chemical Structure

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab120797 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Functional Studies Use at an assay dependent concentration.

画像

  • Functional assays: Caspase 8 (active) FITC Staining Kit (ab65614)

    Active caspase 8 in control Jurkat cells (10e6/mL) or cells treated for five hours with 10 ug/mL Cyclohexamide (CHX) (ab120093) or four hours with 25 ug/mL Mitomycin C (MitoC) (ab120797). Background signal subtracted, duplicates; +/- SD.

参考文献

This product has been referenced in:

  • Mladenov E  et al. Activation of the S phase DNA damage checkpoint by mitomycin C. J Cell Physiol 211:468-76 (2007). Read more (PubMed: 17167777) »
  • Park IC  et al. Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95-independent manner in human gastric adenocarcinoma cells. Cancer Lett 158:125-32 (2000). Read more (PubMed: 10960761) »
  • Sasaki M  et al. Re-evaluation of tumor-specific cytotoxicity of mitomycin C, bleomycin and peplomycin. Anticancer Res 26:3373-80 (0). Read more (PubMed: 17094455) »

レビューと Q&A

There are currently no Customer reviews or Questions for ab120797.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

登録