製品の概要

  • 製品名
    Mitochondrial Staining Reagent - Green - Cytopainter
    Mitochondria キット 製品一覧
  • サンプルの種類
    Adherent cells, Suspension cells
  • アッセイタイプ
    Cell-based (qualitative)
  • 種交差性
    交差種: Mammals, Other species
  • 製品の概要

    Abcam's Mitochondrial Staining Reagent - Green | Cytopainter (ab176830) is part of a series of new fluorogenic probes to label mitochondria of live cells. The proprietary mitochondria dye selectively accumulates in mitochondria probably via the mitochondrial membrane potential gradient. The mitochondrial indicator is a hydrophobic compound that easily permeates intact live cells and becomes trapped in mitochondria after it gets into cells. The fluorescent mitochondrial indicator is retained in mitochondria for a long time since it carries a cell-retaining group. This key feature significantly increases the staining efficiency; make it useful for a variety of studies, including cell adhesion, chemotaxis, multidrug resistance, cell viability, apoptosis and cytotoxicity.


    Review other dyes and kits for mitochondrial staining, or the live cell staining fluorescent dyes guide

  • 特記事項

    Mitochondria are membrane-enclosed organelles found in most eukaryotic cells. Mitochondria are sometimes described as "cellular power plants" because they generate most of the cellular supply of ATP. In addition to supplying cellular energy, mitochondria are involved in a range of other processes, such as signaling, cellular differentiation, cell death, as well as the control of the cell cycle and cell growth. Mitochondria have been implicated in several human diseases, including mitochondrial disorders and cardiac dysfunction, and may play a role in the aging process. Although most of a cellular DNA is contained in the cell nucleus, the mitochondrion has its own independent genome.

  • 試験プラットフォーム
    Fluorescence microscope

製品の特性

画像

  • Image of U2OS cells stained with Abcam's CytoPainter MitoGreen Indicator Reagent (ab176830) in a Costar black wall/clear bottom 96-well plate.

プロトコール

参考文献

This product has been referenced in:
  • Huang CC  et al. Autophagy-Regulated ROS from Xanthine Oxidase Acts as an Early Effector for Triggering Late Mitochondria-Dependent Apoptosis in Cathepsin S-Targeted Tumor Cells. PLoS One 10:e0128045 (2015). Read more (PubMed: 26029922) »
See 1 Publication for this product

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