Metergoline, 5-HT receptor antagonist (ab120526)
Key features and details
- Potent 5-HT receptor antagonist
- CAS Number: 17692-51-2
- Soluble in DMSO to 100 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
-
製品名
Metergoline, 5-HT receptor antagonist -
製品の詳細
Potent 5-HT receptor antagonist -
生理活性の詳細
Potent 5-HT1, 5-HT2 and 5-HT7 receptor antagonist (Ki = 16 nM at h5-HT7 receptor). Additionally displays activity at dopamine receptors. Elicits cell death.
-
CAS 番号
17692-51-2 -
構造式
製品の特性
-
体系名
[(8β)-1,6-(Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester -
分子量
403.52 -
分子式
C25H29N3O2 -
PubChem 登録番号
28693 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM and in ethanol to 50 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES 線形表記
O=C(OCc1ccccc1)NC[C@@H]3C[C@@H]4c5cccc2c5c(cn2C)C[C@H]4N(C)C3 -
由来
Synthetic
-
研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (0)
ab120526 は論文での使用が確認できていません。