製品の概要

  • 製品名

    Medetomidine hydrochloride, alpha2 adrenoceptor agonist
  • 製品の詳細

    Selective α2 adrenoceptor agonist
  • 生理活性の詳細

    Selective α2 adrenoceptor agonist (Ki values for receptor subtypes are 3.89 (α2A), 7.40 (α2B), 12.3 (α2C) and 0.76 nM (α2D)). Crosses the blood-brain barrier. Potent sedative, hypnotic and analgesic properties in vivo.
  • 精製度

    > 99%
  • CAS 番号

    86347-15-1
  • 構造式

    Chemical Structure

製品の特性

  • 体系名

    4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride
  • 分子量

    236.74
  • 分子式

    C13H16N2.HCl
  • 保存方法

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • 溶解性

    Soluble in water to 100 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • 由来

    Synthetic

  • 研究分野

参考文献

This product has been referenced in:

  • Schwartz DD & Clark TP Affinity of detomidine, medetomidine and xylazine for alpha-2 adrenergic receptor subtypes. J Vet Pharmacol Ther 21:107-11 (1998). Read more (PubMed: 9597647) »
  • Cullen LK Medetomidine sedation in dogs and cats: a review of its pharmacology, antagonism and dose. Br Vet J 152:519-35 (1996). Read more (PubMed: 8885463) »

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