Anti-Measles nucleoprotein 抗体 (ab23974)
製品の概要
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製品名Anti-Measles nucleoprotein antibody
Measles nucleoprotein 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to Measles nucleoprotein
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由来種Rabbit
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アプリケーション適用あり: ELISA, WBmore details
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種交差性Reacts with Measles virus. Not yet tested in other species.
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免疫原
Recombinant full length protein.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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バッファーPreservative: None
Constituents: Whole serum -
精製度Whole antiserum
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab23974 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ELISA | 1/2000 - 1/10000. | |
| WB | 1/200 - 1/1000. Predicted molecular weight: 58 kDa. |
ターゲット情報
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関連性Involved in the encapsidating of the genome in a ratio of 1 N per 6 ribonucleotides, resulting in the protection from nucleases. The nucleocapsid (NC) has an helical structure with either 12.35 or 11.64 N per turn, approximately 20nm in diameter, with a hollow central cavity approximately 5nm in diameter. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. N is released in the blood following lysis of measles infected cells, it interacts then with human FCGR2B on immune cells, inducing apoptosis and blocking inflammatory immune response. Ntail binds to a protein on human thymic epithelial cells, termed Nucleoprotein Receptor (NR), inducing growth arrest
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細胞内局在Virion. Host cytoplasm.
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別名
- Measles nucleocapsid protein antibody
- N antibody
- NP antibody
- Nucleocapsid protein antibody
プロトコール
参考文献
This product has been referenced in:
- Hanauer JR et al. Enhanced lysis by bispecific oncolytic measles viruses simultaneously using HER2/neu or EpCAM as target receptors. Mol Ther Oncolytics 3:16003 (2016). WB . Read more (PubMed: 27119117) »
- Stewart CE et al. Inhibitors of the interferon response enhance virus replication in vitro. PLoS One 9:e112014 (2014). Read more (PubMed: 25390891) »
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"