Anti-MDC 抗体 (ab7362)

Submit a review Q&A (1)

Key features and details

  • Rabbit polyclonal to MDC
  • Reacts with: Mouse, Rat
  • Isotype: IgG

製品の概要

  • 製品名

    Anti-MDC antibody
    MDC 一次抗体 製品一覧

  • 製品の詳細

    Rabbit polyclonal to MDC

  • 由来種

    Rabbit

  • 種交差性

    交差種: Mouse, Rat

  • 免疫原

    Recombinant full length protein (Mouse).

  • ポジティブ･コントロール

    • Recombinant human MDC protein (ab638) can be used as a positive control in WB.

  • 特記事項

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

製品の特性

  • 製品の状態

    Liquid

  • 保存方法

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • バッファー

    Preservative: 0.1% Sodium azide
    Constituent: PBS
  • Concentration information loading...

  • 精製度

    Protein A purified

  • ポリ/モノ

    ポリクローナル

  • アイソタイプ

    IgG

  • 研究分野

ターゲット情報

  • 機能

    May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.

  • 組織特異性

    Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis, allergic contact dermatitis skin, and psoriasis, in both the epidermis and dermis.

  • 配列類似性

    Belongs to the intercrine beta (chemokine CC) family.

  • 翻訳後修飾

    The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes.

  • 細胞内局在

    Secreted.
  • Information by UniProt

  • 参照データベース

    • 別名

      • A 152E5.1 antibody
      • ABCD 1 antibody
      • ABCD1 antibody
      • C C motif chemokine 22 antibody
      • CC chemokine STCP 1 antibody
      • CC chemokine STCP-1 antibody
      • ccl 22 antibody
      • Ccl22 antibody
      • CCL22_HUMAN antibody
      • Chemokine (C C motif) ligand 22 antibody
      • DC/B CK antibody
      • DCBCK antibody
      • Macrophage-derived chemokine antibody
      • MDC antibody
      • MDC(1-69) antibody
      • MDC(7-69) antibody
      • MGC34554 antibody
      • SCYA22 antibody
      • Small inducible cytokine subfamily A (Cys Cys) member 22 antibody
      • Small inducible cytokine subfamily A, member 22 antibody
      • Small-inducible cytokine A22 antibody
      • STCP 1 antibody
      • STCP1 antibody
      • Stimulated T cell chemotactic protein 1 antibody
      • Stimulated T-cell chemotactic protein 1 antibody
      see all

    参考文献 (0)

    ab7362 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab7362 は論文での使用が確認できていません。

    レビューと Q&A

    Show All レビュー Q&A
    レビューを送る 質問を送る

    Question

    Hello, Just wanted to know if this antibody has been tested for immunohistochemistry use on formalin fixed paraffin embedded mouse tissue. If so, please could you give any information which may be of help ie what concentration to use and is antigen retrieval required? Thank You Jamie.

    Read More
    Answer

    This antibody has not yet been tested for use with paraffin embedded tissue.

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com