Anti-MD2 抗体 [4H1] (ab106132)
Key features and details
- Mouse monoclonal [4H1] to MD2
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-MD2 antibody [4H1]
MD2 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [4H1] to MD2 -
由来種
Mouse -
特異性
Reacts with both the monomeric and polymeric forms of soluble Human MD2 and the MD2/Toll-like receptor 4 complex. Able to inhibit LPS binding to MD2. It does not cross-react with Mouse MD2. -
種交差性
交差種: Human
非交差種: Mouse -
免疫原
Baculovirally expressed His tagged Human MD2.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Constituents: 0.1% BSA, PBS -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
ab106132 was 0.2 µm filtered prior to formulation. -
ポリ/モノ
モノクローナル -
クローン名
4H1 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
ターゲット情報
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機能
Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS. -
翻訳後修飾
N-glycosylated; high-mannose. -
細胞内局在
Secreted > extracellular space. - Information by UniProt
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参照データベース
- Entrez Gene: 23643 Human
- Omim: 605243 Human
- SwissProt: Q9Y6Y9 Human
- Unigene: 726603 Human
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別名
- ESOP 1 antibody
- ESOP-1 antibody
- ESOP1 antibody
see all
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (0)
ab106132 は論文での使用が確認できていません。
